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http://dx.doi.org/10.3389/fpsyt.2015.00040 | DOI Listing |
Ecancermedicalscience
February 2021
Human-Relevant Infection Biology Group, Institute of Bioinformatics and Biotechnology, Savitribai Phule Pune University, Pune 411007, India.
A wide range of microbes inhabit the oral cavity, and bacterial and fungal communities most often exist as structured communities or biofilms. The use of tobacco alters the structure of the oral microbiome, including that of potentially malignant lesions, and the altered oral microbiome influences key microenvironmental changes such as chronic inflammation, secretion of carcinogenic toxins, cellular and tissue remodelling and suppression of apoptosis. Given this, it is clear that the bacterial and fungal biofilms in potentially malignant states are likely not passive entities, but could play a critical role in shaping potential malignant and carcinogenic conditions.
View Article and Find Full Text PDFFront Psychiatry
March 2015
School of Health Sciences and Psychology, Federation University Australia, Ballarat, VIC , Australia.
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