Hypothesis: Dispersion or aggregation of ceramic nanoparticles in suspension is mainly influenced by their surface properties. The preparation of hydrophobic/hydrophilic nanoparticles was studied by synthesizing for the first time fluorinated Janus particles via a Pickering emulsion method.
Experiments: Fluorinated silica Janus particles were synthesized with a "grafting to" method using silica/wax emulsions. The parameters investigated to control the emulsion were (i) the SiO2 particles/wax ratio, (ii) the cetyltrimethylammonium bromide (CTAB)/SiO2 ratio and (iii) the ionic strength, i.e. NaCl concentration. Prior to grafting with fluorinated molecules, the partially wax-embedded silica particles were functionalized with an aminosilane. Fourier Transformed Infrared and Nuclear Magnetic Resonance spectroscopies, thermogravimetric and zeta potential analyzes were conducted to characterize the fluorinated Janus particles.
Findings: Silica quantity has an influence on the silica nanoparticles distribution at the surface of the wax solid droplets. CTAB amount controls the size and shape of silica/wax solid droplets, whereas the ionic strength in the range 0-6.22 g L(-1) does not influence the silica/wax emulsion. Aminosilane functionalization was successfully employed on partially wax-embedded silica particles, followed by a grafting step with a carboxylic acid fluorinated compound.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.jcis.2015.03.011 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Boric acid-substituted phthalocyanine/ciprofloxacin co-assembled nanoparticles for constructing bacteria-responsive intelligent wound dressings with synergistic therapy and recognition of bacterial infections.
Int J Biol Macromol
January 2025
Key Laboratory of Optic-electric Sensing and Analytical Chemistry for Life Science, Ministry of Education, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, China; Department of Rehabilitation Medicine, Affiliated Qingdao Central Hospital of Qingdao University, Qingdao Cancer Hospital, Qingdao, Shandong 266000, China. Electronic address:
In contemporary times, the waning effectiveness of antibiotics against bacterial infections is progressively giving rise to significant concerns in public health. Although photodynamic technology possesses a potent ability to deactivate bacteria, its non-selective attack on normal cells poses potential side effects. Hence, in this study, a boric acid-substituted phthalocyanine photosensitizer (BAPc) was synthesized, exhibiting remarkable bacterial targeting capability.
View Article and Find Full Text PDFMultifunctional DNA-Collagen Biomaterials: Developmental Advances and Biomedical Applications.
ACS Biomater Sci Eng
January 2025
J. Crayton Pruitt Family Department of Biomedical Engineering, University of Florida, Gainesville, Florida 32611, United States.
The complexation of nucleic acids and collagen forms a platform biomaterial greater than the sum of its parts. This union of biomacromolecules merges the extracellular matrix functionality of collagen with the designable bioactivity of nucleic acids, enabling advances in regenerative medicine, tissue engineering, gene delivery, and targeted therapy. This review traces the historical foundations and critical applications of DNA-collagen complexes and highlights their capabilities, demonstrating them as biocompatible, bioactive, and tunable platform materials.
View Article and Find Full Text PDFA Multifunctional MIL-101-NH(Fe) Nanoplatform for Synergistic Melanoma Therapy.
Int J Nanomedicine
January 2025
Department of Pharmacy, The Affiliated Hospital, Southwest Medical University, Luzhou, Sichuan, 646000, People's Republic of China.
Background: Melanoma is an aggressive form of skin cancer, and single-modality treatments often fail to prevent tumor recurrence and metastasis. Combination therapy has emerged as an effective approach to improve treatment outcomes.
Methods: In this study, we developed a multifunctional nanoplatform, MIL@DOX@ICG, utilizing MIL-101-NH(Fe) as a carrier to co-deliver the chemotherapeutic agent doxorubicin (DOX) and the photosensitizer indocyanine green (ICG).
Selective In Situ Analysis of Hepatogenic Exosomal microRNAs via Virus-Mimicking Multifunctional Magnetic Vesicles.
Adv Healthc Mater
January 2025
The Institute of Chinese Medicine of Nanjing University, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing University Drum Tower Hospital Clinical College, Nanjing University of Chinese Medicine, Nanjing, 210008, China.
Drug-induced liver injury (DILI) is a common clinical problem with urgent respect to demanding early diagnosis. Exosomal miRNAs are reliable and noninvasive biomarkers for the early diagnosis of DILI. However, accurate and feasible detection of exosomal miRNAs is often hampered by the low abundance of miRNAs, inefficient exosome separation techniques, and the requirement for RNA extraction from large sample volumes.
View Article and Find Full Text PDFUrchin-like magnetic nanoparticles loaded with type X collagen siRNA and Stattic to treat triple negative breast cancer under rotating magnetic field like an "enchanted micro-scalpel".
Int J Biol Macromol
January 2025
Institute for Special Environmental Biophysics, Key Laboratory for Space Bioscience and Biotechnology, School of Life Sciences, Northwestern Polytechnical University, Xi'an 710100, Shaanxi, PR China; Research & Development Institute of Northwestern Polytechnical University in Shenzhen, Shenzhen 518063, PR China. Electronic address:
Magnetic nanoparticles effectively target drug delivery, contrast agents, biosensors, and more. Urchin-like magnetic nanoparticles (UMN) with abundant spike-like structures exhibit superior magneto-mechanical force to destroy tumor cells compared with other shapes of magnetic nanoparticles. However, when cell contents are released from tumor cells induced by magneto-mechanical force, they can act on surrounding tumor cells to facilitate tumor development.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!