AI Article Synopsis
- Chronic arsenic exposure leads to various health issues, including skin conditions, heart disease, respiratory problems, and diabetes.
- A 24-year-old woman with a history of chronic arsenic exposure was admitted for progressive shortness of breath, identified as pulmonary arterial hypertension (PAH).
- After ruling out other potential causes of PAH—like chronic obstructive pulmonary disease and genetic factors—the case suggests a link between PAH and chronic arsenic exposure, which is not previously documented.
Article Abstract
Chronic arsenic exposure causes cutaneous effects like hyperkeratosis, peripheral vascular disease, hypertension, ischemic heart disease, non-cirrhotic portal hypertension, hepatomegaly, peripheral neuropathy, respiratory involvement, bad obstetrical outcome, hematological disturbances, and diabetes mellitus. Here we present a case of a 24-year-old lady, with chronic exposure to arsenic, presenting to us with progressive dyspnea. We found pulmonary arterial hypertension (PAH) as a cause of her dyspnea. PAH can occur in arsenicosis, secondary to arsenic-induced chronic obstructive pulmonary disease (COPD), lung fibrosis, and portal hypertension, which we excluded by appropriate investigations in our case. We also excluded a familial or heritable form of PAH. Thus, with the exclusion of all these secondary causes of PAH, as well as a hereditary cause, we came to a conclusion that this PAH might be due to chronic arsenic exposure. To the best of our knowledge, no case of PAH in chronic arsenicosis has been reported to date.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372874 | PMC |
| http://dx.doi.org/10.4103/0970-2113.152640 | DOI Listing |
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