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Effect of taurine supplementation on preventing ventilator-associated pneumonia in pediatrics under mechanical ventilation, a randomized controlled double-blind clinical trial.
Front Pediatr
January 2025
Department of Clinical Pharmacy, School of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran.
Introduction: One of the most prevalent healthcare-associated infections in the pediatric intensive care unit is ventilator-associated pneumonia (VAP). VAP not only results in prolonged hospital and intensive care unit (ICU) stays but also imposes higher costs on patients and the healthcare system. Therefore, it is essential to implement preventive measures.
View Article and Find Full Text PDFDual Blood Purification with CytoSorb and oXiris in Managing Recurrent Septic Shock: A Case Report.
Am J Case Rep
January 2025
Department of Anesthesiology and Intensive Care, Legionowo Hospital, Military Institute of Medicine - National Research Institute, Warsaw, Poland.
BACKGROUND Extracorporeal blood purification strategies were recently developed as adjunctive treatments for sepsis. CytoSorb® is an approved medical device designed to reduce blood levels of inflammatory cytokines. The oXiris high-adsorption membrane filter is used in continuous hemofiltration adsorption.
View Article and Find Full Text PDFThe CRP/PAB ratio outperforms the LRINEC score in early diagnosis of Fournier's gangrene.
Surg Pract Sci
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Department of Gastrointestinal and Anal Diseases, Shenyang Coloproctology Hospital, Shenyang, PR China.
Background: Fournier's gangrene (FG) is scarce and potentially fatal disease. Although the Laboratory Risk Indicator for Necrotizing Fasciitis (LRINEC) score was established in 2004, its reliability as a diagnostic tool to differentiate between FG and perianal abscess is still debated. The objective of this study was to assess the reliability of the LRINEC score and other relevant inflammatory markers.
View Article and Find Full Text PDFImpact of Red Cell Exchange Transfusion on Inflammatory Markers in Sickle Cell Disease.
Mediterr J Hematol Infect Dis
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Pediatric Intensive Care Unit, Hospital Professor Doutor Fernando Fonseca, Unidade Local de Saúde Amadora/Sintra, Portugal.
Background: Red Blood Cell Exchange (RBCX) is a common treatment for pediatric sickle cell disease (SCD). Since inflammation with elevated proinflammatory cytokines plays a crucial role in SCD, this study hypothesized that RBCX might lower these cytokines and aimed to assess the impact of this technique on these markers.
Methods: Prospective and observational study of pediatric SCD patients (HbSS genotype) enrolled in a chronic RBCX program at a Portuguese Hospital from October 2022 to August 2024.
Kernel representation-based End-to-End network-enabled decoding strategy for precise and medical diagnosis.
J Hazard Mater
January 2025
School of Computer Science and Technology, Wuhan University of Science and Technology, Wuhan 430070, China; Hubei Province Key Laboratory of Intelligent Information Processing and Real-time Industrial System, Wuhan 430070, China. Electronic address:
Artificial intelligence-assisted imaging biosensors have attracted increasing attention due to their flexibility, allowing for the digital image analysis and quantification of biomarkers. While deep learning methods have led to advancements in biomarker identification, the diversity in the density and adherence of targets still poses a serious challenge. In this regard, we propose CellNet, a neural network model specifically designed for detecting dense targets.
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