Cryptococcosis is infrequent in children, and isolated cryptococcal osteomyelitis is rarely encountered. Here, we describe a 14-year-old patient in remission from T-cell acute lymphoblastic leukemia with osteomyelitis because of Cryptococcus neoformans var. grubii. The patient was effectively treated with antifungal therapy.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4431918 | PMC |
| http://dx.doi.org/10.1097/INF.0000000000000687 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Cryptococcus neoformans osteomyelitis of the radius treatment with antifungal calcium sulphate: A case report and literature review.
Heliyon
October 2024
Department of Orthopedic Surgery, The 909th Hospital, School of Medicine, Xiamen University, Zhangzhou, 363000, Fujian Province, China.
Background: is an opportunistic fungal pathogen widely distributed in nature, commonly found in soil and bird droppings such as pigeons. Cryptococcal osteomyelitis is usually found in immunocompromised patients, in an unusual condition Cryptococcus invades the bone. It usually occurs as a part of disseminated infection and is rarely isolated, and isolated cryptococcal osteomyelitis of the radius is rarer.
View Article and Find Full Text PDFCryptococcus Neoformans Osteomyelitis of the Right Ankle Diagnosed by Metagenomic Next-Generation Sequencing in a HIV-Negative Patient with Tuberculous Lymphadenitis and Pulmonary Tuberculosis: A Case Report and Recent Literature Review.
Infect Drug Resist
September 2024
Department of Tuberculosis, Hangzhou Red Cross Hospital, Hangzhou, People's Republic of China.
Article Synopsis
- This text discusses a rare case of cryptococcal osteomyelitis in a 67-year-old woman, complicated by tuberculosis, that was challenging to diagnose due to its similarity to other lung infections.
- Metagenomic Next-Generation Sequencing (mNGS) was used to accurately identify the infection after a biopsy, confirming the presence of Cryptococcus neoformans through additional tests.
- The case highlights the importance of advanced genomic techniques in diagnosing complex infections and shows that cryptococcal osteomyelitis, while rare, can be effectively treated with surgery and antifungal medication.
Cryptococcal Osteomyelitis of the Patella: A Case Report.
JBJS Case Connect
July 2024
Department of Orthopaedic Surgery and Rehabilitation, The University of Texas Medical Branch, Galveston, Texas.
Case: A 38-year-old woman presented to our clinic with right knee pain and difficulty ambulating. After cultures were obtained, a cryptococcal infection of the patella was identified. Subsequent workup revealed previously undiagnosed HIV/AIDS and a disseminated cryptococcal infection.
View Article and Find Full Text PDFDestructive Cryptococcal Osteomyelitis Mimicking Tuberculous Spondylitis.
Am J Case Rep
July 2024
Department of Infectious Diseases, The First College of Clinical Medical Science, China Three Gorges University & Yichang Central People's Hospital, Yichang, Hubei, China.
BACKGROUND Cryptococcosis is an opportunistic fungal infection that typically occurs in patients with compromised immune systems, primarily affecting the respiratory and central nervous systems. However, cryptococcal osteomyelitis is a rare manifestation of cryptococcal infection, characterized by nonspecific clinical features. Here, we present a case of vertebral cryptococcal osteomyelitis in a middle-aged woman and discuss diagnostic approaches.
View Article and Find Full Text PDFOrthopedic Manifestations of Disseminated Cryptococcal neoformans Infection in an Immunocompromised Patient: a Case Report.
J Orthop Case Rep
June 2024
Department of Orthopaedic Surgery, Section of Orthopaedic Trauma and Adult Reconstruction, ProMedica Toledo Hospital, Toledo, OH.
Article Synopsis
- Cryptococcus neoformans is a fungus that primarily affects individuals with weakened immune systems, often leading to meningoencephalitis, but cases of muscle infections are rare.
- A 45-year-old man with extensive cryptococcal infection developed multiple muscle abscesses and osteomyelitis, which led to surgery, an amputation, and ultimately death.
- Increased awareness and rapid diagnosis of orthopedic complications from cryptococcal infections may enhance patient outcomes.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!