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Characteristics and risk factors for infection in patients with ANCA-associated vasculitis: A systematic review and meta-analysis.
Autoimmun Rev
January 2025
Department of Rheumatology and Immunology, Beijing Anzhen Nanchong Hospital, Capital Medical University & Nanchong Central Hospital, The Affiliated Nanchong Central Hospital of North Sichuan Medical College, Nanchong, Sichuan, China; Inflammation and Immunology Key Laboratory of Nanchong City, Nanchong, Sichuan, China; Nanchong Central Hospital, (Nanchong Clinical Research Center), Nanchong, Sichuan, China. Electronic address:
Article Synopsis
- The study aimed to summarize infection characteristics and risk factors in patients with anti-neutrophil cytoplasmic antibody-associated vasculitis (AAV) through a comprehensive analysis of relevant research articles.
- In total, 41 studies involving over 5,000 AAV patients revealed that over half experienced some form of infection, with respiratory infections being the most prevalent and severe infections affecting around 35.8% of patients.
- Key risk factors included older age, underlying health conditions (like diabetes and end-stage renal disease), and specific treatments (like cyclophosphamide and high glucocorticoid doses), highlighting the need for careful management and awareness of common infections in AAV patients.
Clinical characteristics and outcomes of invasive pulmonary aspergillosis in renal transplant recipients: A single-center experience.
Transpl Immunol
November 2024
Department of Organ Transplantation, Renmin Hospital of Wuhan University, Wuhan 430060, China. Electronic address:
Objective: This study aimed to explore the clinical features, early diagnostic methods, and therapeutic approaches for invasive pulmonary aspergillosis (IPA) in patients after renal transplantation (RT).
Methods: We retrospectively examined 22 patients who were diagnosed with IPA post-RT and treated at our institution between 2005 and 2024.
Results: Patients had an average age of 46.
Hemorrhages and risk factors in patients undergoing thromboprophylaxis in a respiratory critical care unit: a secondary data analysis of a cohort study.
J Intensive Care
October 2024
Department of Respiratory and Critical Care Medicine, Beijing Institute of Respiratory Medicine and Beijing Chao-Yang Hospital, Capital Medical University, 8 Gongren Tiyuchang Nanlu, Chaoyang District, Beijing, 100020, China.
Objective: To verify whether the bleeding risk assessment guidelines from the 9th American College of Chest Physicians (ACCP) are prognostic for respiratory intensive care unit (RICU) patients and to explore risk factors for hemorrhages, we conducted a secondary data analysis based on our previously published cohort study of venous thromboembolism.
Patients And Methods: We performed a secondary data analysis on the single-center prospective cohort from our previous study. Patients admitted to the RICU at Beijing Chao-Yang Hospital from August 1, 2014 to December 31, 2020 were included and followed up until discharge.
[Medical clinical diagnostics for indoor mould exposure - Update 2023 (AWMF Register No. 161/001)].
Pneumologie
October 2024
Labor Dr. Wisplinghoff.
This article is an abridged version of the updated AWMF mould guideline "Medical clinical diagnostics in case of indoor mould exposure - Update 2023", presented in July 2023 by the German Society of Hygiene, Environmental Medicine and Preventive Medicine (Gesellschaft für Hygiene, Umweltmedizin und Präventivmedizin, GHUP), in collaboration with German and Austrian scientific medical societies, and experts. Indoor mould growth is a potential health risk, even if a quantitative and/or causal relationship between the occurrence of individual mould species and health problems has yet to be established. There is no evidence for a causal relationship between moisture/mould damage and human diseases, mainly because of the ubiquitous presence of fungi and hitherto inadequate diagnostic methods.
View Article and Find Full Text PDFInvestigation of risk factors for invasive pulmonary aspergillosis among patients with COVID-19.
Sci Rep
September 2024
Department of Infectious Diseases, Qilu Hospital of Shandong University, Wenhua Xi Road 107, Jinan, 250012, Shandong, China.
Article Synopsis
- COVID-19 associated pulmonary aspergillosis (CAPA) poses high mortality risks, prompting a study to identify its risk factors among 114 COVID-19 patients.
- The study compared demographics, underlying conditions, lab results, and treatment plans between patients who developed CAPA and those who did not.
- Key independent risk factors for CAPA found were elevated IL-6 levels, decreased CD4+ T cells, and prolonged mechanical ventilation, highlighting the need for early antifungal treatment to improve patient outcomes.
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