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Internal carotid artery aneurysm causing Horner's syndrome with the Harlequin sign.
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Harlequin sign due to an upper thoracic paravertebral lesion. A systematic review of the literature.
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Department of Neurosurgery, University of Arizona College of Medicine, Phoenix, AZ, USA.
Article Synopsis
- Harlequin syndrome (HS) is a rare condition that results in uneven flushing and sweating, often due to issues with the sympathetic nervous system. When it's linked to external damage, it's called Harlequin Sign.
- *In a systematic review of the literature, researchers analyzed 1,538 studies, finding 8 case reports of Harlequin Sign associated with upper thoracic paravertebral lesions, primarily in middle-aged females.
- *The study identified that symptoms like hemifacial flushing and anhidrosis were common, and while CT scans were mainly used for diagnosis, surgical intervention was only successful in resolving symptoms for a quarter of the patients.
Recognition of a patient with neck autonomic dysfunction: findings from a rare case report of harlequin syndrome in direct access physiotherapy.
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December 2024
Department of Occupation and Health, School of Organisation and Development, HAN University of Applied Sciences, Nijmegen, the Netherlands.
Background: Harlequin syndrome is a rare autonomic condition consisting of unilateral facial flushing and sweating induced by heat, emotion or physical activity. The affected side presents anhidrosis and midline facial pallor due to denervation of the sympathetic fibers.
Case Description: This case describes a patient who reported right-side redness of the face associated with hyperhidrosis during physical activity.
Harlequin sign associated with Horner syndrome secondary to an 11 cm left upper lung lobe adenocarcinoma.
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Horner Syndrome With a Positive Harlequin Sign in an Adolescent Male.
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College of Medicine (MDT), University of Saskatchewan, Saskatoon, Canada ; and Division of Ophthalmology (LOT), Department of Surgery, University of Saskatchewan, Regina, Canada.
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