For 50 years, hypotonic solutions have been used as liquid of maintenance in paediatrics owing to the article of Holliday and Segar. For two decades, studies have shown that these hypotonic fluids can foster the acquisition of hyponatremias. The most recent literature data (meta-analysis and randomized studies) confirm that hypotonic fluids are not suitable for children hospitalized with surgical or medical problems. Current recommendations must take these results into account and advocate the use of isotonic saline solutions as maintenance intravenous fluid therapy.
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