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Background: Several studies have been conducted quantifying the impact of schistosome infections on health and development in school-aged children. In contrast, relatively little is known about morbidity levels in preschool-aged children (≤ 5 years) who have been neglected in terms of schistosome research and control. The aim of this study was to compare the utility of available point-of-care (POC) morbidity diagnostic tools in preschool versus primary school-aged children (6-10 years) and determine markers which can be used in the field to identify and quantify Schistosoma haematobium-related morbidity.
Methods/principal Findings: A comparative cross-sectional study was conducted to evaluate the performance of currently available POC morbidity diagnostic tools on Zimbabwean children aged 1-5 years (n=104) and 6-10 years (n=194). Morbidity was determined using the POC diagnostics questionnaire-based reporting of haematuria and dysuria, clinical examination, urinalysis by dipsticks, and urine albumin-to-creatinine ratio (UACR). Attributable fractions were used to quantify the proportion of morbidity attributable to S. haematobium infection. Based on results of attributable fractions, UACR was identified as the most reliable tool for detecting schistosome-related morbidity, followed by dipsticks, visual urine inspection, questionnaires, and lastly clinical examination. The results of urine dipstick attributes showed that proteinuria and microhaematuria accounted for most differences between schistosome egg-positive and negative children (T=-50.1; p<0.001). These observations were consistent in preschool vs. primary school-aged children.
Conclusions/significance: Preschool-aged children in endemic areas can be effectively screened for schistosome-related morbidity using the same currently available diagnostic tools applicable to older children. UACR for detecting albuminuria is recommended as the best choice for rapid assessment of morbidity attributed to S. haematobium infection in children in the field. The use of dipstick microhaematuria and proteinuria as additional indicators of schistosome-related morbidity would improve the estimation of disease burden in young children.
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http://dx.doi.org/10.1371/journal.pntd.0003649 | DOI Listing |
Int J Speech Lang Pathol
December 2024
Faculty of Rehabilitation Medicine, College of Health Sciences, University of Alberta, Edmonton, Canada.
Purpose: Assessment allows speech-language pathologists to identify clients' strengths and needs while laying the foundation for the therapeutic relationship. However, the extent to which parents' experiences with assessment has been explored in the literature is unclear. The purposes of this review were to: a) Identify and summarise the available literature on parents' experiences with speech-language assessment for their preschool-aged children, and b) identify gaps in the literature.
View Article and Find Full Text PDFActa Trop
December 2024
Swiss Tropical and Public Health Institute, Allschwil, Switzerland; University of Basel, Basel, Switzerland.
Pediatric schistosomiasis in hard-to-reach communities is poorly understood, hampering tailored interventions. This study investigated the prevalence, intensity, health impact, and risk factors for schistosomiasis in preschool-aged children (PSAC) residing in hard-to-reach areas and populations of Homa Bay County, Kenya. A cross-sectional study was conducted among 476 PSAC aged 2-5 years across 6 islands in Lake Victoria, Homa Bay County, Kenya.
View Article and Find Full Text PDFChild Psychiatry Hum Dev
December 2024
Lifespan Health and Wellbeing Centre, Macquarie University, Sydney, NSW, 2109, Australia.
There are few psychometrically sound measures of overprotection designed for the caregiver and focusing largely on overt behaviours and actions. The Parental Overprotection Measure (POM) was developed for research with preschool aged children and has been used in a range of research projects and translated into several languages. However, its full psychometric properties have not previously been reported.
View Article and Find Full Text PDFInt J Obes (Lond)
December 2024
Department of Food and Nutrition, University of Helsinki, Helsinki, Finland.
Background/objectives: Circadian health plays an important role in overall well-being. The objective of this study was to examine whether potential indicators of circadian disruption, such as exhibiting a later chronotype or greater social jetlag, in preschool-age could predict dietary habits or BMI z-scores in an eight-year follow-up.
Subjects/methods: Our data included 210 children who participated in the DAGIS Survey in 2015-2016 (baseline, mean [SD] age: 4.
PLOS Glob Public Health
December 2024
Swiss Tropical and Public Health Institute, Allschwil, Switzerland.
A new formulation of praziquantel, arpraziquantel (arPZQ), has been developed for preschool-aged children (PSAC) to fill the treatment gap for this age group in schistosomiasis control and elimination programs. There is now a priority to ensure that the drug reaches all at-risk PSAC in endemic areas, including hard-to-reach areas and populations. This study aimed to determine schistosomiasis treatment-related contextual factors among fishermen and island populations in Homa Bay County, Kenya, and to identify a suitable platform to deliver arPZQ.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!