AI Article Synopsis
- The study aimed to distinguish between atypical subacute thyroiditis and malignant thyroid nodules using sonographic features.
- A total of 165 hypoechoic thyroid nodules were analyzed, with nodules categorized into thyroiditis (55 nodules) and malignancy (110 nodules) groups.
- Key findings indicated that poorly defined margins were more common in the thyroiditis group and proved to be effective for diagnosis, while specific echogenic changes were unique to the thyroiditis group, providing some diagnostic value.
Article Abstract
Objectives: The purpose of this study was to evaluate sonographic features for distinguishing clinically atypical subacute thyroiditis from malignant thyroid nodules.
Methods: A total of 165 hypoechoic thyroid nodules without calcification in 135 patients with histologic diagnosis were included in this study. These nodules were classified into 2 groups: a thyroiditis group (55 nodules in 36 patients) and a malignancy group (110 nodules in 99 patients). The sonographic features of the groups were retrospectively reviewed.
Results: No significant differences were detected for the variables of marked echogenicity, a taller-than-wide shape, and mixed vascularity. However, a poorly defined margin was detected more frequently in the thyroiditis group than the malignancy group (P < .05); it yielded a high capability for differential diagnosis of atypical subacute thyroiditis, with sensitivity and specificity of 87.3% and 80.9%, respectively. Centripetal reduction echogenicity was observed exclusively in the thyroiditis group, with high specificity (100%) but low sensitivity (21.8%) for atypical subacute thyroiditis diagnosis. All of the thyroiditis nodules with a positive color signal showed noninternal vascularity (negative predictive value, 100%).
Conclusions: There is a considerable overlap between the sonographic features of atypical subacute thyroiditis and thyroid malignancy. However, the margin, echogenicity, and vascularity type are helpful indicators for differential diagnosis of atypical subacute thyroiditis.
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| http://dx.doi.org/10.7863/ultra.34.4.689 | DOI Listing |
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