Treatment of asymptomatic bacteriuria contributes to antimicrobial overuse in hospitalized patients. Indications for urine culture, treatment, and targets for improvement were evaluated in 153 patients. Drivers of antimicrobial overuse included fever with an alternative source, altered mental status, and leukocytosis, which led 435 excess days of antimicrobial therapy.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1017/ice.2014.73 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Prevalence and risk factors of antibiotic resistance for urinary tract infections in patients presenting to a Belgian tertiary care emergency department: testing the national guidelines against the local setting.
Acta Clin Belg
January 2025
Internal Medicine department, UZ Brussel, Internal Medicine Research Group, Vrije Universiteit Brussel, Brussels, Belgium.
Objectives: Urinary tract infections (UTIs) are an important cause of empiric antibiotic (over)treatment at the emergency department (ED). To enhance empiric antibiotic choices, mapping the national and local microbiology and antimicrobial resistance (AMR) patterns is crucial. This study aims to examine resistance patterns at a Brussels ED and to identify risk factors for AMR to evaluate current treatment guidelines and help combat AMR.
View Article and Find Full Text PDFEvolving Enterococcus faecalis Biofilms and Urinary Tract Infection Relapse: Does Vaginal Estrogen Matter?
Urogynecology (Phila)
December 2024
Department of Obstetrics and Gynecology, Hackensack Meridian Jersey Shore Medical Center, Neptune, NJ.
Importance: Enterococcus faecalis urinary tract infection (UTI) is common in postmenopausal females and these bacteria create biofilms that may reduce treatment efficacy. The role of local vaginal estrogen therapy in susceptibility to E. faecalis infection is unclear.
View Article and Find Full Text PDFDe-implementation strategy to reduce overtreatment of asymptomatic bacteriuria in the emergency department: a stepped-wedge cluster randomised trial.
Ther Adv Infect Dis
December 2024
Internal Medicine, Infectious Diseases, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
Article Synopsis
- Asymptomatic bacteriuria (ASB) is the presence of bacteria in urine without urinary tract infection symptoms, and treating it is generally not helpful.
- The study aimed to lower unnecessary antibiotic treatment for ASB in emergency departments (EDs) in the Netherlands using an educational and feedback-based strategy.
- Results showed a decrease in urinalyses ordered and a reduction in treatment duration for ASB patients, but there was no significant drop in the inappropriate use of antibiotics.
Validation and generalizability of an asymptomatic bacteriuria metric in critical access hospitals.
Infect Control Hosp Epidemiol
December 2024
Division of General Internal Medicine, Department of Internal Medicine, University of Utah, Salt Lake City, UT, USA.
Article Synopsis
- The study aimed to adapt the Inappropriate Diagnosis of UTI (ID-UTI) measure for use in Critical Access Hospitals (CAHs), assessing its feasibility, validity, and reliability.
- Only 40% of participating CAHs met the target for case submissions, with the ID-UTI metric showing high specificity (100%) but low sensitivity (48.5%) compared to physician reviews.
- While the adapted measure was reliable (93% agreement), challenges remain in ensuring its consistent application across CAHs.
The rise, fall, and resurgence of phage therapy for urinary tract infection.
EcoSal Plus
December 2024
Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA.
In the face of rising antimicrobial resistance, bacteriophage therapy, also known as phage therapy, is seeing a resurgence as a potential treatment for bacterial infections including urinary tract infection (UTI). Primarily caused by uropathogenic , the 400 million UTI cases annually are major global healthcare burdens and a primary cause of antibiotic prescriptions in the outpatient setting. Phage therapy has several potential advantages over antibiotics including the ability to disrupt bacterial biofilms and synergize with antimicrobial treatments with minimal side effects or impacts on the microbiota.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!