AI Article Synopsis
- Tripterygium wilfordii contains complex chemical components with significant potential for anti-inflammatory and immunoregulatory effects.
- Over the past 30 years, research has identified over ten active monomers with these properties, highlighting its pharmacological significance.
- Further studies are needed on specific compounds such as wilforidine, triptolidenol, triptonide, and demethylzeylasteral to understand their pharmacology and toxicology better.
Article Abstract
Tripterygium wilfordii has complex chemical components. To study and summarize the advance in studies on the anti-inflammatory and immunoregulatory activities and toxicology of known monomers of T. wilfordii, the pertinent literatures related to the studies on the pharmacology, toxicology and pharmacokinetics of T. wilfordii over past 30 years were searched. According to the findings, more than ten anti-inflammatory and immunoregulatory monomers were found in T. wilfordii. The pharmacology and toxicology of wilforidine, triptolidenol, triptonide, demethylzeylasteral shall be further studied.
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