Think beyond the Skin: 2014 Canadian Expert Opinion Paper on Treating to Target in Plaque Psoriasis.

J Cutan Med Surg

Faculty of Medicine, Division of Dermatology, Memorial University, St. John's NLDepartment of Medicine, Division of Dermatology, University of Toronto, Toronto, ON and Lynderm Research Inc., Markham, ONDepartment of Dermatology and Skin Science, Child and Family Research Institute, University of British Columbia, Vancouver, BCDepartment of Medicine, McMaster University, Hamilton ON, Service of Dermatology, St. Joseph's Hospital, Hamilton, ON and Dermatrials Research, Dermatology Centre, Hamilton, ONDivision of Dermatology, Department of Medicine, University of Toronto, Toronto, ONFaculty of Medicine, Sherbrooke University, Sherbrooke, QCDepartment of Medicine, Division of Dermatology, Laval University, Quebec, QCDepartment of Dermatology and Skin Science, University of British Columbia, Vancouver, BCDepartment of Medicine, Division of Dermatology, University of Alberta, Edmonton, AB and Searles Dermatology & Aesthetics, Edmonton, ABCHUQ, Hotel-Dieu Hospital, Laval University, Quebec, QC.

Published: September 2015

Objective: Explore the feasibility of Treat to Target in the area of psoriasis as seen in other therapeutic areas such as hypertension, hyperlipidemia, diabetes and rheumatoid arthritis.

Methods: Review validated, measurable targets for psoriasis, including physician global assessment (PGA), psoriasis area and severity index (PASI) and dermatology life quality index (DLQI). Examine principles brought forth in the published European consensus on psoriasis and develop a Canadian consensus on Treat to Target in psoriasis.

Results: As PASI and DLQI are not routinely used in the community setting, we are recommending target at a PGA of zero (clear).

Conclusion: Recommend that the target is a PGA of zero (clear) as it provides a simple and measurable result that the patient and physician can clearly understand.

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Source
http://dx.doi.org/10.2310/7750.2014.13151DOI Listing

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