The personal and societal importance of genetics has increased dramatically since the 1950s, but most introductory courses still focus on teaching students how to think like geneticists, training them in Mendelian and molecular analysis. This article is a personal account of a new course with a different goal, giving students knowledge and skills that they can use in their nonacademic lives. Useful Genetics differs from typical courses in emphasizing personal genomics, natural genetic and phenotypic variation in humans, and the consequences of genetic inheritance for breeding, inbreeding, and ancestry. Although it is a Massive Open Online Course (MOOC), taught to large global populations of learners of all ages and backgrounds, it maintains the academic rigor of a college course. The course materials are freely available for reuse by other instructors, and are being used as the foundation of a face-to-face university credit course.
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Comparison of the natural course of clinical and radiologic features in 13 patients with TRPV4-related skeletal dysplasias.
Pediatr Radiol
January 2025
Department of Pediatric Genetics, Istanbul University-Cerrahpaşa, Cerrahpasa Medical Faculty, 34098, Cerrahpasa, Istanbul, Turkey.
Background: Heterozygous TRPV4 mutations cause a group of skeletal dysplasias characterized by short stature, short trunk, and skeletal deformities.
Objective: The aim of this study is to compare the natural history of clinical and radiologic features of patients with different TRPV4-related skeletal dysplasias.
Materials And Methods: Thirteen patients with a mutation in TRPV4 were included in the study, and 11 were followed for a median of 6.
Interpersonal space is regulated carefully and updated dynamically during social interactions to maintain comfort. We investigated the naturalistic processing of interpersonal distance in real time and space using a powerful implicit neurophysiological measure of attentional engagement. In a sample of 37 young adults recruited at a UK university, we found greater EEG alpha band suppression when a person occupies or moves into near personal space than for a person occupying or moving into public space.
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