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Similar Publications

Unlabelled: Pancreatic masses are extremely rare in pediatric patients, with limited data available. This lack of data makes the diagnosis and management of these tumors in children extremely challenging. Therefore, we aimed to describe the presentations, clinical course, and outcomes of children with pancreatic tumors at our center.

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Middle-segment preserving pancreatectomy: a literature review and case report.

Langenbecks Arch Surg

June 2024

Hepato-Biliary-Pancreatic Surgery Division, Department of Surgery, National Center for Global Health and Medicine, 1-21-1 Toyama, Shinjuku-ku, Tokyo, 162-8655, Japan.

Article Synopsis
  • Middle segment-preserving pancreatectomy (MSPP) is a newer surgical option for treating benign and borderline pancreatic diseases, offering an alternative to total pancreatectomy (TP), with only 36 reported cases so far.
  • In a case study of a 49-year-old man with Zollinger-Elison syndrome, MSPP was successfully performed, resulting in a postoperative pancreatic fistula that improved with conservative care, and no tumor recurrence was observed.
  • Although MSPP has a high morbidity rate (54%) primarily due to complications like pancreatic fistula, it shows low mortality rates and maintains pancreatic function similar to traditional surgeries.
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This case study reports a rare case of a non-functioning metastatic pancreatic neuroendocrine tumor (pNET) transforming into a functioning pNET. A 59-year-old male, previously treated with distal pancreatectomy, splenectomy, lymph node dissection, liver metastasectomy, and pharmacotherapy, presented with weakness, hypoglycemia, and daily episodes of watery diarrhea. A functioning neuroendocrine liver metastasis expressing insulin and gastrin was identified.

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Article Synopsis
  • - Gastrinoma leads to excess gastrin production, resulting in increased gastric acid and recurring health issues like peptic ulcers and chronic diarrhea, coupled with complications such as esophageal strictures.
  • - A case study illustrates a patient with gastrinoma who faced refractory benign esophageal stricture (RBES) and complete esophageal blockage, despite various treatments aimed at reducing acid secretion.
  • - Early diagnosis of gastrinoma is crucial; prolonged uncontrolled acid can significantly heighten the risk of severe esophageal strictures, making treatment options like endoscopic procedures risky and complex.
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Article Synopsis
  • Primary gallbladder gastrinoma is a rarely reported neuroendocrine tumor, with no known prior cases documented in medical literature.
  • A case study details a 50-year-old woman who experienced watery diarrhea and was later diagnosed with a tumor located at the gallbladder neck, confirmed during laparoscopic surgery.
  • The study emphasizes the importance of immunohistochemical analysis for diagnosis and suggests that surgical removal can successfully alleviate symptoms, contributing new insights into this uncommon condition.
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