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Reinventing type 2 immunity in cancer.
Nature
January 2025
Laboratory for Immune Cell Systems, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.
Our understanding of type 2 immunity has undergone a substantial transformation in recent years, revealing previously unknown functions. Beyond its canonical role in defence against parasitic helminth infections, type 2 immunity safeguards the host through additional mechanisms, including the suppression of excessive type 1 immune responses, regulation of tissue repair and maintenance of adipose tissue homeostasis. However, unlike type 1 immune responses, type 2 immunity is perceived as a potential promoter of tumorigenesis.
View Article and Find Full Text PDFMorphoDiff: Cellular Morphology Painting with Diffusion Models.
bioRxiv
December 2024
Department of Computer Science, University of Toronto, Toronto, ON, Canada.
Understanding cellular responses to external stimuli is critical for parsing biological mechanisms and advancing therapeutic development. High-content image-based assays provide a cost-effective approach to examine cellular phenotypes induced by diverse interventions, which offers valuable insights into biological processes and cellular states. In this paper, we introduce MorphoDiff, a generative pipeline to predict high-resolution cell morphological responses under different conditions based on perturbation encoding.
View Article and Find Full Text PDFA hybrid attention generative adversarial network for Chinese landscape painting.
Sci Rep
January 2025
School of Software, Pingdingshan University, Pingdingshan, 467000, China.
In traditional Chinese painting, the genre of landscapes is unique and universally valued. For an untrained person to achieve such results is very difficult, requiring mastery of such things as brushwork, composition, and color. In this paper, we propose HA-GAN to transform sketches into Chinese landscape paintings, a new GAN-based framework that builds upon a hybrid attention generator and a discriminator.
View Article and Find Full Text PDFApplication of style transfer algorithm in the integration of traditional garden and modern design elements.
PLoS One
December 2024
AnnLab, Institute of Semiconductors, Chinese Academy of Sciences, Beijing, China.
Article Synopsis
- - The study investigates how modern design elements can blend with traditional garden aesthetics using style transfer algorithms to create innovative and sustainable garden designs.
- - Experiments showcased the successful integration of traditional landscape paintings' aesthetics into virtual scenes, specifically using the Humble Administrator's Garden as a case study.
- - This research highlights the potential for technology to enhance garden design by marrying cultural heritage with new methods, paving the way for future preservation and innovative applications in urban cultural heritage.
What drives the development of digital rural life in China?
Heliyon
November 2024
School of agriculture, Orient science & technology college of Hunan Agricultural University, Hunan, 400125, China.
Background And Objective: Empowering rural life through digital technology reflects the collective aspirations of millions of farmers striving for a better quality of life. Ensuring that the benefits of digital advancements reach every corner of the population is a crucial and inevitable choice. To expedite the establishment of an inclusive digital life for all citizens, the Chinese government has exerted substantial efforts by positioning the development of digital villages as a national strategy.
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