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Embracing Nature's Wisdom: Liposome-Mediated Amplification of Electrochemiluminescence for the Sensitive and Selective Immunoassay of Serum Amyloid A.
Anal Chem
January 2025
School of Environmental and Biological Engineering, Nanjing University of Science and Technology, Nanjing 210094, P R China.
Serum amyloid A (SAA) is a key biomarker for diagnosing inflammatory responses in diseases like influenza and COVID-19. An electrochemiluminescence (ECL) biosensor has been constructed for signal enhancement in SAA detection by encapsulating 4,4',4″,4‴-(1,3,6,8-pyrenetetrayl) tetrakis-benzoic acid (TBAPy) into liposomes. Such biomimetic encapsulation shields the biologically important membrane to avoid aggregation of TBAPy and prevents quenching.
View Article and Find Full Text PDFPermeable, Stretchable, and Recyclable Cellulose Aerogel On-Skin Electronics for Dual-Modal Sensing and Personal Healthcare.
ACS Nano
January 2025
CAS Key Laboratory of Mechanical Behavior and Design of Materials, Department of Modern Mechanics, University of Science and Technology of China, Hefei, Anhui 230027, PR China.
Flexible on-skin electronics present tremendous popularity in intelligent electronic skins (e-skins), healthcare monitoring, and human-machine interfaces. However, the reported e-skins can hardly provide high permeability, good stretchability, and large sensitivity and are limited in long-term stability and efficient recyclability when worn on the human body. Herein, inspired from the human skin, a permeable, stretchable, and recyclable cellulose aerogel-based electronic system is developed by sandwiching a screen-printed silver sensing layer between a biocompatible CNF/HPC/PVA (cellulose nanofiber/hydroxypropyl cellulose/poly(vinyl alcohol)) aerogel hypodermis layer and a permeable polyurethane layer as the epidermis layer.
View Article and Find Full Text PDFVaccination as a Promising Approach in Cardiovascular Risk Mitigation: Are We Ready to Embrace a Vaccine Strategy?
Biomolecules
December 2024
Diabetes Center, First Department of Propaedeutic Internal Medicine, Medical School, National and Kapodistrian University of Athens, Laiko General Hospital, 11527 Athens, Greece.
Cardiovascular disease (CVD) remains a leading global health concern, with atherosclerosis being its principal cause. Standard CVD treatments primarily focus on mitigating cardiovascular (CV) risk factors through lifestyle changes and cholesterol-lowering therapies. As atherosclerosis is marked by chronic arterial inflammation, the innate and adaptive immune systems play vital roles in its progression, either exacerbating or alleviating disease development.
View Article and Find Full Text PDFEmbracing New Love: Why Customers Are Loyal to Plant Extract-Based Skin-Care Cosmetics.
J Cosmet Dermatol
January 2025
Department of Bio-Industry Communication and Development, National Taiwan University, Taipei, Taiwan.
Background: In recent years, increases in consumer awareness regarding health and the environment have enhanced their willingness to purchase plant extract-based skin-care products. Although the skin-care product industry has paid increasing attention to consumer behavior in recent years, few studies have investigated customer loyalty to this type of product; in-depth research is urgently required to fill this gap.
Aims: This study investigated Taiwanese skin-care products derived from plant extracts by identifying the relationships between consumer prior experience, involvement, perceived value, and loyalty.
Advancing Treatment for Leishmaniasis: From Overcoming Challenges to Embracing Therapeutic Innovations.
ACS Infect Dis
January 2025
Centre of Experimental Medicine and Surgery, Institute of Medical Sciences Banaras Hindu University, Varanasi-221005, U.P., India.
Protozoan parasite infections, particularly leishmaniasis, present significant public health challenges in tropical and subtropical regions, affecting socio-economic status and growth. Despite advancements in immunology, effective vaccines remain vague, leaving drug treatments as the primary intervention. However, existing medications face limitations, such as toxicity and the rise of drug-resistant parasites.
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