Hepatoprotective benzofurans and furanolignans from Gymnema tingens.

J Asian Nat Prod Res

a State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Chinese Academy of Medical Sciences and Peking Union Medical College, Institute of Material Medica, Beijing 100050 , China.

Published: June 2015

Two new benzofurans, gymnefuranols A (1) and B (2), together with six known furanolignans (3-8), were isolated from Gymnema tingens. The structures of the new compounds were elucidated by comprehensive analysis of the NMR and HR-MS data. Compounds 1, 2, 6, and 7 showed hepatoprotective activities against D-galactosamine-induced HL-7702 cell damage.

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Source
http://dx.doi.org/10.1080/10286020.2015.1016002DOI Listing

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