The principal objectives and problems facing forensic chemistry expertise are considered. In addition, its development as a pharmaceutical discipline, its goals and practical tasks are discussed.
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Anal Bioanal Chem
January 2025
Forensic Laboratory of Biologically Active Substances, Department of Chemistry of Natural Compounds, University of Chemistry and Technology, Technická 5, 166 28, Prague 6, Prague, Czech Republic.
The recent surge in popularity of cannabidiol-infused products extends beyond food and supplements to the cosmetic industry. Accurate labeling remains a significant concern, as many products fail to meet advertised cannabidiol content and/or contain psychoactive tetrahydrocannabinol above the permissible levels. In this work, we present the use of an HPLC-UV-MS/MS method for the quantification of five major cannabinoids (cannabidiol, cannabidiolic acid, tetrahydrocannabinol, tetrahydrocannabinolic acid, and cannabigerol) in oil-in-water cosmetic emulsions.
View Article and Find Full Text PDFPharmacol Res
January 2025
Jena University Hospital, Department of Anesthesiology and Intensive Care Medicine, Friedrich-Schiller-University Jena, Jena, Germany; Jena University Hospital, Center for Sepsis Control and Care, Friedrich-Schiller-University Jena, Jena, Germany; Friedrich-Schiller-University Jena, Faculty of Medicine, Jena, Germany. Electronic address:
Sepsis is a life-threatening organ failure resulting from a poorly regulated infection response. Organ dysfunction includes hepatic involvement, weakening the immune system due to excretory liver failure, and metabolic dysfunction, increasing the death risk. Although experimental studies correlated excretory liver functionality with immune performance and survival rates in sepsis, the proteins and pathways involved remain unclear.
View Article and Find Full Text PDFProc Natl Acad Sci U S A
January 2025
The Martin (Szusz) Department of Land of Israel Studies and Archaeology, Institute of Archaeology, Bar-Ilan University, Ramat Gan 5290002, Israel.
In contrast to animal foods, wild plants often require long, multistep processing techniques that involve significant cognitive skills and advanced toolkits to perform. These costs are thought to have hindered how hominins used these foods and delayed their adoption into our diets. Through the analysis of starch grains preserved on basalt anvils and percussors, we demonstrate that a wide variety of plants were processed by Middle Pleistocene hominins at the site of Gesher Benot Ya'aqov in Israel, at least 780,000 y ago.
View Article and Find Full Text PDFForensic Sci Int Synerg
June 2025
Département de Chimie, Biochimie et Physique, Université du Québec à Trois-Rivières, 3351 boul. des Forges, Trois-Rivières, Québec, G8Z 4M3, Canada.
The detection of skeletal remains using human remain detection dogs (HRD) is often reported anecdotally by handlers to be a challenge. Limited studies have been conducted to determine the volatile organic compounds (VOCs) emitted from bones, particularly when there is limited organic matter remaining. This study aimed to determine the VOCs emitted from dry, weathered bones and examine the detection performance of HRD dogs on these bones when used as training aids.
View Article and Find Full Text PDFMed Sci Educ
June 2024
Medicolegal Institute, Ibn Rochd University Hospital,, Casablanca, Morocco.
Background: This scoping review aimed to explore the existing literature on teaching clinical reasoning in the field of forensic medicine.
Methods: The scoping review was conducted following the PRISMA extension for scoping reviews.
Results: The initial search yielded a total of 98 articles, of which 40 studies met the inclusion criteria.
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