According to the working principle of vertical ultrasonic vial washing machine, receiving respective force of small water droplets on the inside wall of vials and the minimum air velocity of blowing off water droplets can be obtained based on the analysis of water-droplet-related parameters. The inside wall model of 7 mL vial created by GAMBIT was divided into fine grids. Then the Realizable k-epsilon Two Equation Turbulence Model was adopted and the flow field of vial by FLUENT software was simulated when air was flushing inside the wall. In that case, the optimal position, inner diameter and the corresponding minimum air velocity of needle can be acquired to meet the needs of vial washing machine applied to 7 mL vial.
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Microsyst Nanoeng
August 2024
BIOS/Lab on a Chip Group, Max Planck Center Twente for Complex Fluid Dynamics, University of Twente, Enschede, The Netherlands.
Functionalized monodisperse microbubbles have the potential to boost the sensitivity and efficacy of molecular ultrasound imaging and targeted drug delivery using bubbles and ultrasound. Monodisperse bubbles can be produced in a microfluidic flow focusing device. However, their functionalization and sequential use require removal of the excess lipids from the bubble suspension to minimize the use of expensive ligands and to avoid competitive binding and blocking of the receptor molecules.
View Article and Find Full Text PDFClin Chim Acta
April 2024
Department of Pharmacology and Toxicology, Raymond Poincaré Hospital, GHU AP-HP.Paris-Saclay, 92380 Garches, France; Paris-Saclay University, UVSQ, Inserm U-1018, CESP, Team MOODS, Plateform MasSpecLab, 78180 Montigny-le-Bretonneux, France.
Ostarine, also known as MK-2866 or enobosarm, is a selective androgen receptor modulator (SARM). It has anabolic properties and as such is widely used in doping, accounting in 2021 for 25 % of the adverse analytical findings (AAF) among the class S1.2 "Other anabolic agents" of products banned by the World Anti-Doping Agency, to which it belongs.
View Article and Find Full Text PDFNucl Med Biol
March 2024
Division of Nuclear Medicine, Department of Radiology, University of Michigan, 1301 Catherine St. 2276 Medical Science I, Ann Arbor, MI 48109, United States of America. Electronic address:
Introduction: Increased demand for NetSpot and Illuccix as requirement to receive the respective Lutathera and Pluvicto radiotherapies, and monitor subsequent response to treatment, have reinforced the need to develop alternative ways of producing gallium-68 (Ga). Building on our efforts to produce Ga in a liquid target on a GE PETtrace, the goal of this work is to modify the current GE Gallium Chloride cassette using the FASTLab 2 synthesis module to produce [Ga]GaCl equivalent to a 1.85 GBq generator and demonstrate compatibility with FDA-approved kits for production of Ga-labeled radiopharmaceuticals.
View Article and Find Full Text PDFIntroduction: Liquid-based cytology (LBC) has replaced conventional smear (CS) in the world. In this study, through a series with a large number of cases, we aimed to make a comparison and general evaluation in all groups, primarily epithelial abnormalities, according to LBC and CS methods. This study was carried out in a private pathology laboratory located in a metropolitan city, where cytological materials sent from many clinics were examined.
View Article and Find Full Text PDFAdv Mater
August 2024
Material Science and Engineering Program, College of Engineering and Applied Science, University of Colorado Boulder, Boulder, CO, 80303, USA.
Volumetric additive manufacturing (VAM) is an emerging layerless method for the rapid processing of reactive resins into 3D structures, where printing is much faster (seconds) than other lithography and direct ink writing methods (minutes to hours). As a vial of resin rotates in the VAM process, patterned light exposure defines a 3D object and then resin that has not undergone gelation can be washed away. Despite the promise of VAM, there are challenges with the printing of soft hydrogel materials from non-viscous precursors, including multi-material constructs.
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