Recent functional studies have unveiled the significant role chromatin topology plays in gene regulation. Several lines of evidence suggest genes access necessary factors for transcription by forming chromatin loops. A clearer picture of the players involved in chromatin organization, including lncRNA, is emerging.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4215167 | PMC |
| http://dx.doi.org/10.4161/trns.28658 | DOI Listing |
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