We report for the first time a case of ovarian strumal carcinoid containing both trabecular carcinoid and mucinous glands lined by both goblet and neuroendocrine cells and a low-grade mucinous neoplasm that presented clinically as pseudomyxoma peritonei in the absence of appendiceal lesion in a 58-yr-old woman. Histologically, there were both a tall columnar cell epithelial component lacking neuroendocrine cells, showing the scalloped contours and subepithelial clefts of low-grade appendiceal-type neoplasms and a mixed goblet cell neuroendocrine element. Characteristically, both reproduced appendiceal neoplastic phenotypes in a teratoid fashion. In addition, we present previously unreported oncocytic and mucinous changes in the thyroideal components of strumal carcinoid. This case represents a rare instance of pseudomyxoma peritonei of primary ovarian origin and is an example of multiple somatic teratoid endodermal differentiations of the different sections of the embryonal gut: foregut represented by thyroid, midgut by both mucinous appendiceal components, and hindgut by trabecular carcinoid.

Download full-text PDF

Source
http://dx.doi.org/10.1097/PGP.0000000000000138DOI Listing

Publication Analysis

Top Keywords

strumal carcinoid
12
pseudomyxoma peritonei
12
ovarian strumal
8
trabecular carcinoid
8
neuroendocrine cells
8
carcinoid
5
mucinous
5
carcinoid appendiceal-type
4
appendiceal-type mucinous
4
mucinous tumor
4

Similar Publications

Management strategy of primary ovarian mucinous carcinoid tumor: A rare case report.

Medicine (Baltimore)

September 2024

Department of Obstetrics and Gynecology, Kyung Hee University College of Medicine, Kyung Hee University Medical Center, Seoul, Korea.

Article Synopsis
  • Primary ovarian carcinoid tumors are very rare, with only about 30 cases reported since they were first identified in 1939; they can be classified into various types, with mucinous forms being extremely uncommon.
  • A 40-year-old woman experienced lower abdominal pain for three months, and imaging revealed a significant soft tissue mass, leading to laparoscopic surgery for diagnosis and treatment.
  • After being diagnosed with a primary ovarian mucinous carcinoid tumor and receiving treatment, the patient's symptoms improved, highlighting the importance of surgical intervention and the need for further research on postoperative chemotherapy.
View Article and Find Full Text PDF

Ovarian carcinoid is a rare well-differentiated neuroendocrine tumor resembling those arising in the gastrointestinal tract. We present a case of ovarian carcinoid with magnetic resonance imaging (MRI) findings. A 50-year-old woman with genital bleeding and severe constipation was referred to our hospital.

View Article and Find Full Text PDF

Introduction: Ovarian strumal carcinoid is a rare type of germ cell tumor. It usually affects perimenopausal and postmenopausal women. Very few cases of stromal carcinoid have been reported in the literature in women of childbearing age, particularly during pregnancy.

View Article and Find Full Text PDF

Neoplasms in Struma Ovarii: A Review.

Endocr Pathol

December 2023

Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA, 19104, USA.

Struma ovarii is a well-known ovarian teratoma made up of benign thyroid tissue. These lesions demonstrate variable, normal architecture and normal thyroid immunohistochemical staining with positivity for TTF1, PAX8, and thyroglobulin. Though most are benign, some of these lesions can also present with a malignant component.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!