AI Article Synopsis
- Endometriosis is a significant health issue for women of reproductive age, with delayed diagnosis being a major challenge for effective treatment.
- A blood test that could detect endometriosis-specific biomarkers is needed for quicker and more accurate diagnosis, but no reliable noninvasive options have been established yet.
- Micro-RNAs are being investigated as potential biomarkers for endometriosis diagnosis, though their effectiveness and limitations still need careful consideration.
Article Abstract
Endometriosis represents a major medical concern in women of reproductive age. One of the remaining major hurdles for successful treatment of endometriosis is the limitation of the process of timely disease diagnosis. A simple blood test for endometriosis-specific biomarkers would offer a more timely accurate diagnosis for the disease, thus allowing for earlier treatment intervention. Although there have been considerable efforts to identify such biomarkers, no clear choice for such noninvasive diagnostic tools has been identified. Micro-RNAs are small noncoding RNAs that have been evaluated intensively as biomarkers for several diseases, and they may hold promise for a diagnosis of endometriosis. In this review, we highlight the need for noninvasive testing for endometriosis, discuss the potential use of micro-RNAs as diagnostic tools for this disease, and consider potential limitations in the use of these small RNA molecules as diagnostic markers for endometriosis.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4489990 | PMC |
| http://dx.doi.org/10.1016/j.jmig.2015.02.021 | DOI Listing |
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