Expression data analysis with Reactome.

Curr Protoc Bioinformatics

European Bioinformatics Institute (EMBL-EBI), European Molecular Biology Laboratory, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom.

Published: March 2015

The Reactome database of curated biological pathways provides a tool for visualizing user-supplied expression data as an overlay on pathway diagrams, thereby affording an effective means to examine expression of the constituents of the pathway and determine whether all that are necessary are present. Several experiments can be visualized in succession, to determine whether expression changes with experimental conditions, a useful feature for examining a time-course, dose-response, or disease progression.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4407007PMC
http://dx.doi.org/10.1002/0471250953.bi0820s49DOI Listing

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