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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4335301 | PMC |
| http://dx.doi.org/10.3389/fpsyg.2015.00163 | DOI Listing |
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Research on truck-drone collaborative route planning for rural logistics delivery services.
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Department of Production Engineering, KTH Royal Institute of Technology, 11428, Stockholm, Sweden.
This study investigates the implementation of collaborative route planning between trucks and drones within rural logistics to improve distribution efficiency and service quality. The paper commences with an analysis of the unique characteristics and challenges inherent in rural logistics, emphasizing the limitations of traditional methods while highlighting the advantages of integrating truck and drone technologies. It proceeds to review the current state of development for these two technologies and presents case studies that illustrate their application in rural logistics.
View Article and Find Full Text PDFHuman migration from the Levant and Arabia into Yemen since Last Glacial Maximum.
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College of Medicine and Health Sciences, Khalifa University, Abu Dhabi, United Arab Emirates.
While a broad consensus about the first successful migration modern humans out of Africa seems established, the peopling of Arabia remains somewhat enigmatic. Identifying the ancestral populations that contributed to the gene pool of the current populations inhabiting Arabia and the impact of their contributions remains a challenging task. We investigate the genetic makeup of the current Yemeni population using 46 whole genomes and 169 genotype arrays derived from Yemeni individuals from all geographic regions across Yemen and 351 genotype arrays derived from neighboring populations providing regional context.
View Article and Find Full Text PDFTriterpene esters from Uncaria rhynchophylla hooks as potent HIV-1 protease inhibitors and their molecular docking study.
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Department of Pharmacognosy, College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul, 08826, Korea.
Despite significant advancements with combination anti-retroviral agents, eradicating human immunodeficiency virus (HIV) remains a challenge due to adverse effects, adherence issues, and emerging viral resistance to existing therapies. This underscores the urgent need for safer, more effective drugs to combat resistant strains and advance acquired immunodeficiency syndrome (AIDS) therapeutics. Eight triterpene esters (1-8) were identified from Uncaria rhynchophylla hooks.
View Article and Find Full Text PDFD-loop mutations in mitochondrial DNA are a risk factor for chemotherapy resistance in esophageal cancer.
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Department of Gastroenterological Surgery, Graduate School of Medicine, Osaka University, 2-2-E2, Yamada-Oka, Suita, Osaka, 565-0871, Japan.
Esophageal cancer is a highly aggressive disease, and acquired resistance to chemotherapy remains a significant hurdle in its treatment. mtDNA, crucial for cellular energy production, is prone to mutations at a higher rate than nuclear DNA. These mutations can accumulate and disrupt cellular function; however, mtDNA mutations induced by chemotherapy in esophageal cancer remain unexplored.
View Article and Find Full Text PDFDeep learning models reveal the link between dynamic brain connectivity patterns and states of consciousness.
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BAOBAB Unit, NeuroSpin center, CEA, Université Paris-Saclay, Gif-sur-Yvette, France.
Decoding states of consciousness from brain activity is a central challenge in neuroscience. Dynamic functional connectivity (dFC) allows the study of short-term temporal changes in functional connectivity (FC) between distributed brain areas. By clustering dFC matrices from resting-state fMRI, we previously described "brain patterns" that underlie different functional configurations of the brain at rest.
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