AI Article Synopsis
- The study aimed to evaluate the effectiveness of sentinel lymph node (SLN) biopsy techniques in early head and neck cancer patients, comparing indocyanine green (ICG) alone, radioisotope (RI) alone, and their combination.
- Nineteen patients participated, with detection times measured for each method, revealing that the combination of ICG and RI identified more SLNs and had a shorter mean detection time compared to RI alone.
- The conclusion highlights that using both ICG and RI together improves the identification speed and accuracy of SLNs in surgical procedures.
Article Abstract
Aim: This study was designed to assess the validity of sentinel lymph node (SLN) biopsy using either the combination of indocyanine green (ICG) fluorescence and radioisotope (RI) or ICG-alone in SLN mapping for early head and neck cancer patients.
Patients And Methods: Nineteen patients received SLN biopsy with the following method. Thirteen patients received SLN biopsy with only RI, 2 patients with only ICG and 4 patients with the combination of ICG and RI. Detection time for each method of SLN biopsy was measured to evaluate the validity of SLN with the combination of ICG and RI.
Results: A total of 41 SLNs were identified by RI or ICG. All SLNs identified by ICG could be localized intraoperatively. The number of SLNs identified by the combination of ICG and RI was greater than that of SLNs identified by RI-alone. One of the patients who underwent SLN biopsy by RI-alone was diagnosed with a metastatic lymph node one year later, then underwent neck dissection. Mean detection time for SLN biopsy with ICG or with the combination of ICG and RI tended to be shorter than that of RI-alone.
Conclusion: SLN biopsy with the combination of ICG and RI enabled us to identify SLNs more easily and rapidly than by using RI alone.
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