AI Article Synopsis

  • Transcatheter closure of patent ductus arteriosus (PDA) is increasingly recognized as the standard treatment, showing high success rates, though outcomes can differ between pediatric cardiology centers.
  • A retrospective study at Cipto Mangunkusumo Hospital, Jakarta, from 2002 to 2013 reviewed data from 298 patients, finding a median age of 3.4 years and a successful device deployment in all cases, mostly using the Amplatzer ductal occluder.
  • The procedure demonstrated high efficacy with 97.3% achieving complete closure, minimal complications reported, and most patients discharged after just one day.

Article Abstract

Transcatheter closure of patent ductus arteriosus (PDA) has been suggested to be the standard treatment of PDA. Although, in general, the procedure shows a high successful rate, outcomes may vary among pediatric cardiology centers. To evaluate the effectiveness of transcatheter closure of PDA in Cipto Mangunkusumo Hospital, Jakarta, Indonesia, this was a retrospective study on patients who underwent transcatheter closure of PDA in Cipto Mangunkusumo Hospital during the period of 2002-2013. Hospital registry was reviewed and data about patients' characteristics, PDA severity, procedure, and outcomes were retrieved. There were 298 patients, of whom 90 were males, who underwent transcatheter closure of PDA during the study period. Median age was 3.4 years (1 months-18 years), and median body weight was 12 (3.6-59) kg. The diameter of PDA ranged from 1.1 to 15.4 mm with a median of 3.7 mm. Device could be deployed in all patients, in which most were the Amplatzer ductal occluder (69.8 %) and the remainders were coils. Median fluoroscopy time was 15.4 (1.5-87) min, and procedure time was 76 (30-200) min. Complete closure was achieved in most patients (97.3 %), whereas device migration occurred in a minority (0.3 %) of patients. No major complication occurred during or after the procedure. Transient anemia and bradycardia were found in 3.7 and 1.3 % patients, respectively. Most patients were discharged from the hospital at 1 day after the procedure. Transcatheter closure method is a safe and effective procedure to close PDA.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4432078PMC
http://dx.doi.org/10.1007/s00246-015-1128-2DOI Listing

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