This paper discusses a general method for the use of orthogonal polynomials for unequal intervals (OPUI) to eliminate interferences in two-component spectrophotometric analysis. In this paper, a new approach was developed by using first derivative D1 curve instead of absorbance curve to be convoluted using OPUI method for the determination of metronidazole (MTR) and nystatin (NYS) in their mixture. After applying derivative treatment of the absorption data many maxima and minima points appeared giving characteristic shape for each drug allowing the selection of different number of points for the OPUI method for each drug. This allows the specific and selective determination of each drug in presence of the other and in presence of any matrix interference. The method is particularly useful when the two absorption spectra have considerable overlap. The results obtained are encouraging and suggest that the method can be widely applied to similar problems.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.saa.2015.01.076 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Research Paradigm of the International Classification of Functioning, Disability and Health (ICF) With Item Response Theory: Clarification, Classification, and Challenge.
Physiother Res Int
January 2025
Center of Rehabilitation Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Background: The International Classification of Functioning, Disability and Health (ICF) is the worldwide terminology system for measuring health and disability at both individual and population levels. However, the underlying challenges remain in achieving widespread adoption and implementation of ICF within healthcare contexts, including the unequal interval scale of the ICF Likert-type qualifier system ranging from 0 to 4, a lack of consensus on conceptualization and grading criteria of ICF items, and an excessive number of ICF items associated with each disease. The utilization of item response theory (IRT) for ICF studies demonstrated potential benefits in addressing these issues.
View Article and Find Full Text PDFTrends and cross-country inequality in the incidence of GI cancers among the working-age population from 1990 to 2021: a Global Burden of Disease 2021 analysis.
Gut
December 2024
Division of Gastroenterology and Hepatology, Shanghai Institute of Digestive Disease, NHC Key Laboratory of Digestive Diseases, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
Background: GI cancers pose an increasing global health burden, with their impact on the working-age population (WAP) aged 15-64 years remaining largely unexplored despite the crucial role of this group in societal and economic well-being.
Objective: To assess trends and cross-country inequality in the global burden of six GI cancers from 1990 to 2021 among individuals in the WAP.
Design: The 2021 Global Burden of Disease study dataset was used to obtain estimates of GI cancer incidence and 95% uncertainty intervals, including the number of cases, crude incidence rate and age-standardised incidence rate (ASIR).
Optimal vaccination policy to prevent endemicity: a stochastic model.
J Math Biol
December 2024
Département de Mathématiques, Université du Québec à Montréal, Montréal, Canada.
We examine here the effects of recurrent vaccination and waning immunity on the establishment of an endemic equilibrium in a population. An individual-based model that incorporates memory effects for transmission rate during infection and subsequent immunity is introduced, considering stochasticity at the individual level. By letting the population size going to infinity, we derive a set of equations describing the large scale behavior of the epidemic.
View Article and Find Full Text PDFGender Gap in Academic Surgery: Disparities in Early-Career Scholarly Productivity Sets the Stage for Unequal Academic Advancement.
J Surg Res
December 2024
Division of Surgical Oncology, Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey; Department of Health, Behavior and Policy, Rutgers School of Public Health, Piscataway, New Jersey. Electronic address:
Introduction: Gender disparities exist in academic surgery despite advances in the field. This study aimed to examine the extent of gender disparities in career advancement and promotion among academic faculty in surgery and understand the influence of academic productivity.
Methods: Cross-sectional study using publicly available information from online faculty profiles of 18 large academic US general surgery residency programs.
Evaluation of low-and middle-income countries according to cardiovascular disease risk factors by using pythagorean fuzzy AHP and TOPSIS methods.
BMC Med Inform Decis Mak
November 2024
Department of Industrial Engineering, Faculty of Engineering, Ondokuz Mayıs University, Samsun, Türkiye.
Background: Cardiovascular disease risk factors play a crucial role in determining individuals' future health status and significantly affect health. This paper aimed to address cardiovascular disease risk factors in low- and middle-income countries using multi-criteria decision-making methods.
Methods: In line with this objective, 22 evaluation criteria were identified.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!