AI Article Synopsis
- - An 85-year-old man was diagnosed with colon MALT lymphoma and initially treated by trying to eradicate Helicobacter pylori, which didn't work.
- - After 4 years of no treatment and stable condition, he was lost to follow-up and later developed new lymphoma lesions in the stomach and small intestine, 9 years after the initial diagnosis.
- - Genetic testing revealed a specific fusion gene linked to the lymphoma, indicating it had spread and suggested the need for careful monitoring of multiple lesions in MALT lymphoma cases.
Article Abstract
An 85-year-old man was diagnosed with mucosa-associated lymphoid tissue (MALT) lymphoma of the colon in 20XX. Although Helicobacter pylori eradication was performed as part of the treatment, it was ineffective. He was followed-up by colonoscopy for 4 years without additional treatment and there was no interval change;however, he was lost to follow-up 6 years after the first visit. Nine years after the initial diagnosis, he presented with new MALT lymphoma lesions in the stomach and small intestine. Genetic analysis showed that a biopsy specimen was positive for API2/MALT1 fusion gene, and IgH rearrangement showed monoclonal banding between colon and stomach. This suggested disseminated monoclonal API2/MALT1-positive MALT lymphoma of the colon, stomach, and small intestine. Careful attention should be paid to the appearance of multiple lesions in MALT lymphoma.
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| http://dx.doi.org/10.11405/nisshoshi.112.270 | DOI Listing |
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