Background: Infants with normal fidgety movements at 3 to 5 months after term are very likely to show neurologically normal development, while the absence of fidgety movements is an early marker for an adverse neurological outcome, mainly cerebral palsy (CP). The clinical significance of so-called sporadic fidgety movements (i.e., fidgety movements occur isolated in a few body parts and are of 1- to 3-second-duration) is not yet known.
Aims: Our objective was to determine whether infants who had developed CP and had sporadic fidgety movements have a better outcome than infants who did not have fidgety movements.
Study Design: Longitudinal study. Retrospective analysis of prospectively collected data.
Subjects: 61 infants who developed CP (46 male, 15 female; 29 infants born preterm; videoed for the assessment of movements and postures at 9 to 16 weeks post-term age).
Outcome Measures: The Gross Motor Function Classification System (GMFCS) was applied at 3 to 5 years of age.
Results: There was no difference between children diagnosed with CP who had sporadic fidgety movements at 9 to 16 weeks post-term age (n = 9) and those who never developed fidgety movements (n = 50) with regard to their functional mobility and activity limitation at 3 to 5 years of age. One infant had normal FMs and developed unilateral CP, GMFCS Level I; the remaining infant had abnormal FMs and developed bilateral CP, GMFCS Level II.
Conclusions: There is no evidence that the occurrence of occasional isolated fidgety bursts indicates a milder type of CP.
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http://dx.doi.org/10.1016/j.earlhumdev.2015.02.003 | DOI Listing |
Commun Med (Lond)
January 2025
Child and Adolescent Psychiatry and Psychotherapy, University Medical Center Göttingen, Leibniz ScienceCampus Primate Cognition and German Center for Child and Adolescent Health (DZKJ), Göttingen, Germany.
Background: To assess the integrity of the developing nervous system, the Prechtl general movement assessment (GMA) is recognized for its clinical value in diagnosing neurological impairments in early infancy. GMA has been increasingly augmented through machine learning approaches intending to scale-up its application, circumvent costs in the training of human assessors and further standardize classification of spontaneous motor patterns. Available deep learning tools, all of which are based on single sensor modalities, are however still considerably inferior to that of well-trained human assessors.
View Article and Find Full Text PDFPhys Occup Ther Pediatr
January 2025
Faculty of Physical Therapy and Rehabilitation, Hacettepe University, Ankara, Türkiye.
Aims: Autism Spectrum Disorder (ASD) may exhibit early motor delay, and long-term motor impairments in addition to social and communicative problems. This pilot study aimed to describe (i) the early motor repertoire using General Movements Assessment (GMA) of infants later diagnosed with ASD, (ii) the developmental outcomes in these children between 24- and 42-months, and (iii) the relationship between GMA and developmental outcomes.
Methods: Ten children diagnosed with ASD were included.
Background: The increasing clinical use of combining structural MRI (sMRI) with General Movements Assessment (GMA) or Hammersmith Infant Neurological Exam (HINE) before five months corrected age (CA) for early diagnosis of cerebral palsy (CP) lacks sufficient prognostic data for children with CP, especially those with Gross Motor Function Classification System (GMFCS) I.
Objective: Evaluate the predictive value of sMRI, GMA, and HINE individually and in combination for early CP diagnosis and assess accuracy across varying GMFCS levels in a regional cohort of preterm infants.
Methods: We performed sMRI between 39-44 weeks postmenstrual age and GMA and HINE between 12-18 weeks CA in 395 preterm infants born at ≤32 weeks' gestation across five NICUs in Greater Cincinnati.
Sci Rep
November 2024
Developmental Imaging, MCRI, Melbourne, Australia.
Over the first few months after birth, the typical emergence of spontaneous, fidgety general movements is associated with later developmental outcomes. In contrast, the absence of fidgety movements is a core feature of several neurodevelopmental and cognitive disorders. Currently, manual assessment of early infant movement patterns is time consuming and labour intensive, limiting its wider use.
View Article and Find Full Text PDFJ Pediatr
October 2024
Queensland Cerebral Palsy and Rehabilitation Research Centre, The University of Queensland, Queensland, Australia.
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