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Exploring the safety and feasibility of intracameral Aprokam® (cefuroxime sodium) in pediatric cataract surgery.
Int Ophthalmol
January 2025
Cleveland Clinic Abu Dhabi, Eye Institute, Abu Dhabi, United Arab Emirates.
Purpose: To describe the safety and assess the feasibility of using intracameral cefuroxime sodium (Aprokam®) during congenital cataract surgery as a preventive measure for endophthalmitis.
Design: Monocentric, prospective, observational pilot study.
Setting: San Giuseppe Hospital, University of Milan, Milan, Italy.
Transplanted Heart Complicated by Intracardiac Aspergilloma With Pericardial Involvement.
JACC Case Rep
October 2024
Department of Cardiology, Allegheny General Hospital, Pittsburgh, Pennsylvania, USA.
Article Synopsis
- - The patient, a cardiac transplant recipient, experienced symptoms of right eye pain and blurry vision.
- - Upon investigation, she was diagnosed with intracardiac aspergilloma that affected her pericardium, alongside complications like endogenous endophthalmitis and an acute heart attack.
- - Treatment included a mechanical debulking procedure using the Angiovac system to address the aspergilloma.
Risk factors for endogenous endophthalmitis in infectious endocarditis patients.
Eye (Lond)
January 2025
Institute of Ophthalmology & Visual Science, Rutgers New Jersey Medical School, Newark, NJ, 07103, USA.
Article Synopsis
- The study aimed to identify demographic factors and health conditions that increase the risk of developing endogenous endophthalmitis (EE) in patients with infective endocarditis (IE).
- Analysis of data from 769,472 inpatient cases revealed that older patients (21-64 years) and those identifying as Hispanic or Asian/Pacific Islander had a higher risk of EE, while women made up a slightly higher percentage of EE patients.
- Diabetes (both with and without complications), alcohol use disorder, and cirrhosis were linked to a significantly increased risk of EE, while congestive heart failure and arrhythmia were associated with a lower risk.
Optical coherence tomography-derived texture-based radiomics features identify eyes with intraocular inflammation in the HAWK clinical trial.
Heliyon
July 2024
The Tony and Leona Campane Center for Excellence in Image-Guided Surgery and Advanced Imaging Research, Cole Eye Institute, Cleveland Clinic, Cleveland, OH, USA.
Background And Objective: Intravitreal injection of anti-VEGF agents is the first-line treatment for patients with neovascular-age related macular degeneration (nAMD). One unique serious adverse event that may be associated with these agents is intraocular inflammation (IOI). The main purpose of this analysis was to evaluate the potential presence of texture-based radiomics features characterizing heterogeneity within the vitreous compartment of spectral domain optical coherence tomography (SD-OCT) images that may precede or develop in association with IOI and might serve as OCT biomarkers for IOI.
View Article and Find Full Text PDFWolfram-silicone implants as effective radiation shielding for ocular brachytherapy: dosimetric features and in vivo animal study on biocompatibility.
Can J Ophthalmol
October 2024
Central Animal Laboratory, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
Objective: To evaluate wolfram as a photon and beta absorber in the management of uveal melanoma with radiotherapy, examining its potential ocular adverse effects and physiologic tolerance using an in vivo rabbit ocular model.
Methods: A method of manufacturing implants from mixtures of wolfram and silicone was developed. Their shielding effect on the radiation of sources used in ocular brachytherapy was investigated by dosimetric measurement in an eye phantom as well as numerical simulations.
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