AI Article Synopsis
- - The study details the synthesis of Yanglingmycin, its enantiomer, and eighteen related analogues, confirming their structures primarily through NMR analysis.
- - Antibacterial tests revealed that Yanglingmycin and some analogues were notably effective against two key agricultural pathogens, showing MIC values between 3.91 and 15.62 µg/mL.
- - The promising antibacterial properties of Yanglingmycin and its derivatives indicate their potential for developing new bactericide compounds.
Article Abstract
The synthesis of Yanglingmycin and its enantiomer, along with eighteen Yanglingmycin analogues is reported. The structures were confirmed mainly by analyses of NMR spectral data. Antibacterial activity assays showed that Yanglingmycin and some of its analogues exhibited significant antibacterial activities against two important agricultural pathogenic bacteria, Ralstonia solanacearum and Pseudomonas syringae pv. actinidiae, with minimum inhibitory concentration (MIC) values ranging from 3.91 to 15.62 µg/mL. The antibacterial activities exhibited by Yanglingmycin and its analogues are promising, suggesting potential in the development of compounds for novel bactericides.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1248/cpb.c14-00578 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!