A 74-year-old woman was hospitalized due to dysuria, weakness and dysesthesia of the lower extremities. She was in an immunosuppressed state following the administration of methylprednisolone therapy for idiopathic interstitial pneumonia. Cerebrospinal fluid and blood cultures were negative, and no infectious biomarkers were found. A gadolinium (Gd)-enhanced T1-weighted image of magnetic resonance imaging (MRI) revealed disseminated nodular lesions along the spinal cord. We suspected a diagnosis of seronegative deep mycosis and initiated anti-fungal therapy with voriconazole, which subsequently alleviated all of the patient's symptoms and MRI findings. Therefore, the presence of Gd-enhanced disseminated nodules on spinal MRI may be a good marker of deep meningeal mycosis.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.2169/internalmedicine.54.3148 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Cryptococcal Pneumonia in Multiple Myeloma: A Case Report.
Cureus
December 2024
Hematology Oncology, Miami Cancer Institute, Miami, USA.
Patients with multiple myeloma (MM) often experience infections due to aberrant immunoglobulin production by malignant plasma cells and immunosuppressive therapeutic interventions that are used to treat the condition. A rare but serious infection that may occur in these patients is Cryptococcus, an encapsulated fungus that typically infects immunocompromised individuals. Cryptococcus infections often present as pneumonia but can disseminate to the central nervous system, potentially causing meningitis.
View Article and Find Full Text PDFDisseminated Histoplasmosis With Lung and Liver Involvement in an Immunocompetent Patient.
Cureus
December 2024
Nephrology, Hospital Clinic Barcelona, Barcelona, ESP.
Histoplasmosis, caused by the fungus , is a significant public health concern in endemic regions like Mexico. Immunocompromised individuals, especially those with HIV infection and those exposed to nitrogen-rich environments, such as bird excrement or bat guano, are particularly vulnerable. This case report describes a middle-aged patient with jaundice in the skin and mucous membranes.
View Article and Find Full Text PDFGastric Mixed Neuroendocrine-Non-Neuroendocrine Neoplasm: An Unusual Tumor and Its Presentation in a Young Adult.
GE Port J Gastroenterol
December 2024
Department of Gastroenterology, Hospital de Braga, Braga, Portugal.
Article Synopsis
- Gastric cancer, primarily adenocarcinomas, is a leading cause of cancer death, and mixed neuroendocrine-non-neuroendocrine neoplasm (MiNEN) is one of the rarest subtypes, with significant bleeding occurring in some patients.
- A case study involves a healthy 26-year-old male who had two major gastrointestinal bleeding episodes, leading to the discovery of a 15-mm lesion at the gastroesophageal junction, which was later diagnosed as a mixed adenoneuroendocrine carcinoma.
- Despite its rarity and the lack of established treatment protocols, the patient underwent surgery and chemotherapy, with no evidence of cancer recurrence two years later.
Multifocal Cutaneous Tuberculosis in an Immunocompetent Patient: A Case Report.
Infect Drug Resist
October 2024
Hospital for Skin Diseases, Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing, People's Republic of China.
Cutaneous tuberculosis is an infection caused by , the rare and the bacillus Calmette-Guérin vaccine. This disease has many clinical types with diverse clinical manifestations, mainly includes lupus vulgaris, tuberculosis verrucosa cutis, orificial tuberculosis and scrofuloderma that are difficult to identify. We report a case of cutaneous tuberculosis in a female who presented with disseminated papular and nodular lesions on her face and hands.
View Article and Find Full Text PDFDisseminated Actinomyces Case Report: A Mimicker of Advanced Ovarian Malignancy.
Case Rep Oncol
September 2024
Department of Obstetrics and Gynecology, NYU Langone Health, New York, NY, USA.
Introduction: Disseminated actinomyces is a rare infection that presents with subtle symptoms and radiographic findings. Patients frequently complain of pelvic pain and nonspecific gastrointestinal symptoms. Imaging can reveal a tumor-like mass and mimic malignancy.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!