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Synthesis, structural and antioxidant studies of some novel N-ethyl phthalimide esters. | LitMetric

Synthesis, structural and antioxidant studies of some novel N-ethyl phthalimide esters.

PLoS One

X-ray Crystallography Unit, School of Physics, Universiti Sains Malaysia, Penang, Malaysia; Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.

Published: January 2016

A series of N-ethyl phthalimide esters 4(a-n) were synthesized and characterized by spectroscopic studies. Further, the molecular structure of majority of compounds were analysed by single crystal X-ray diffraction studies. The X-ray analysis revealed the importance of substituents on the crystal stability and molecular packing. All the synthesized compounds were tested for in vitro antioxidant activity by DPPH radical scavenging, FRAP and CUPRAC methods. Few of them have shown good antioxidant activity.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351070PMC
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0119440PLOS

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