Dosimetry of patients submitted to cerebral PET/CT for the diagnosis of mild cognitive impairment.

Radiol Bras

Research Fellow, Titular Researcher, Centro de Desenvolvimento da Tecnologia Nuclear - Comissão Nacional de Energia Nuclear (CDTN-CNEN), Belo Horizonte, MG, Brazil.

Published: March 2015

Objective: The present study was aimed at evaluating the effective radiation dose in patients submitted to PET/CT for the diagnosis of mild cognitive impairment.

Materials And Methods: TLD-100 detectors inserted into an Alderson Rando® anthropomorphic phantom were utilized to measure the absorbed dose coming from the CT imaging modality. The anthropomorphic phantoms (male and female adult versions) were submitted to the same technical protocols for patients' images acquisition. The absorbed dose resulting from the radiopharmaceutical injection was estimated by means of the model proposed by the ICRP publication 106.

Results: The effective dose in patients submitted to this diagnostic technique was approximately (5.34 ± 1.99) mSv.

Conclusion: Optimized protocols for calculation of radioactive activity injected into patients submitted to this diagnostic technique might contribute to reduce the effective radiation dose resulting from PET/CT in the diagnosis of mild cognitive impairment.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4341384PMC
http://dx.doi.org/10.1590/0100-3984.2013.1800DOI Listing

Publication Analysis

Top Keywords

patients submitted
16
pet/ct diagnosis
12
diagnosis mild
12
mild cognitive
12
cognitive impairment
8
effective radiation
8
radiation dose
8
dose patients
8
absorbed dose
8
submitted diagnostic
8

Similar Publications

Background And Purpose: Radiation-induced lymphopenia (RIL) may be associated with a worse prognosis in pancreatic cancer. This study aimed to develop a normal tissue complication probability (NTCP) model to predict severe RIL in patients with pancreatic cancer undergoing concurrent chemoradiotherapy (CCRT).

Materials And Methods: We reviewed pancreatic cancer patients treated at our facility for model training and internal validation.

View Article and Find Full Text PDF

Tumid lupus erythematosus (TLE) is a rare subtype of cutaneous lupus, which can present diagnostic challenges due to its overlapping features with other skin disorders. Understanding the clinical and histopathological characteristics of TLE is essential for accurate diagnosis and management. In this article, we describe a case of TLE in a 45-year-old man who presented with annular, urticarial, non-scarring plaques on the scalp associated with non-scarring alopecia in the affected area.

View Article and Find Full Text PDF

This research explores the types and effectiveness of occlusal splints in managing temporomandibular disorders (TMDs). TMDs encompass a range of musculoskeletal and neuromuscular conditions affecting the jaw, causing pain, limited movement, and discomfort. Occlusal splints, also known as bite guards, are commonly used in dentistry to alleviate TMD symptoms by relaxing jaw muscles, preventing joint trauma, and protecting teeth.

View Article and Find Full Text PDF

When a difficult airway is anticipated, awake tracheal intubation can be considered. Usually, low doses of sedatives are administered during this procedure for minimal sedation and anxiolysis, such as midazolam and remifentanil. The newly developed ultra-short-acting benzodiazepine remimazolam has a pharmacokinetic profile that is more suitable for titration during awake tracheal intubation than the long-acting midazolam.

View Article and Find Full Text PDF

An atrial septal defect (ASD) is a common congenital heart anomaly that results in irregular blood flow between the systemic and pulmonary circulations due to an opening in the atrial septum. Ostium secondum ASD accounts for a large proportion of these defects and often goes unnoticed during childhood and adolescence. Pulmonary hypertension (PH), affecting a significant number of patients with ostium secondum ASD, is associated with functional limitations, heart failure, and tachyarrhythmias.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!