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The association between gestational selective serotonin reuptake inhibitor (SSRI) treatment and newborn thyroid screen: a large-scale cohort study.
BMC Pediatr
January 2025
Institute of Pediatric Endocrinology, Dana Dwek Children's Hospital, Tel Aviv Sourasky Medical Center, 6 Weizmann Street, 6423906, Tel Aviv, Israel.
Background: The diagnosis of depression or anxiety treated by SSRIs has become relatively common in women of childbearing age. However, the impact of gestational SSRI treatment on newborn thyroid function is lacking. We explored the impact of gestational SSRI treatment on newborn thyroid function as measured by the National Newborn Screening (NBS) Program and identified contributory factors.
View Article and Find Full Text PDFEffects of psilocybin on mouse brain microstructure.
AJNR Am J Neuroradiol
January 2025
From the Department of Radiology (P.C.F., A.P.S., J.J.Y.).
Background And Purpose: There is surging interest in the therapeutic potential of psychedelic compounds like psilocybin in the treatment of psychiatric illnesses like major depressive disorder (MDD). Recent studies point to the rapid antidepressant effect of psilocybin; however, the biological mechanisms underlying these differences remain unknown. This study determines the feasibility of using diffusion MRI to characterize and define the potential spatiotemporal microstructural differences in the brain following psilocybin treatment in C57BL/6J male mice.
View Article and Find Full Text PDFAntidepressants versus placebo for generalised anxiety disorder (GAD).
Cochrane Database Syst Rev
January 2025
Department of Psychiatry and Department of Epidemiology and Biostatistics, Western University, St Thomas, Canada.
Background: Generalised anxiety disorder (GAD) is a mental health condition characterised by excessive anxiety and worry about everyday events. GAD is a common disorder and generally affects women twice as often as men. Treatments include various psychological and pharmacological therapies.
View Article and Find Full Text PDFArticle Synopsis
- Smoking is a significant public health issue in Tamil Nadu, causing preventable diseases and increasing healthcare costs, necessitating effective smoking cessation strategies in primary health care (PHC) settings.
- The study aims to evaluate the cost-effectiveness of three proposed smoking cessation strategies against the current standard strategy, focusing on various combinations of counseling, nicotine replacement therapy, and medications for smokers aged 15 and older.
- Results indicated that the current cessation strategy was more expensive than the proposed strategies, with two of them (PS1 and PS3) being more cost-effective, potentially leading to better resource allocation for smoking cessation efforts.
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