Ubiquitination is of great importance as the post-translational modification of proteins with ubiquitin, or ubiquitin chains, facilitates a number of vital cellular processes. Herein we present a facile method of preparing various ubiquitin conjugates under mild conditions using michael acceptors based on dibromo-maleimides and dibromo-pyridazinediones.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372856 | PMC |
| http://dx.doi.org/10.1039/c5ob00130g | DOI Listing |
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