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Fractional flow reserve-guided complete revascularization versus culprit-only percutaneous coronary intervention in patients with myocardial infarction: A meta-analysis of randomized controlled trials.
Cardiovasc Revasc Med
December 2024
Department of Cardiovascular Medicine, Baystate Medical Center and Division of Cardiovascular Medicine, University of Massachusetts-Baystate, Springfield, MA, USA. Electronic address: https://twitter.com/AGoldsweig.
Introduction: The optimal revascularization strategy for patients with myocardial infarction (MI) and multivessel coronary artery disease (CAD) remains an area of research and debate. Fractional flow reserve (FFR)-guided complete revascularization (CR) by percutaneous coronary intervention (PCI) has emerged as an alternative to traditional culprit-only PCI.
Objective: To investigate the outcomes of FFR-guided CR versus culprit-only PCI in patients with MI and multivessel CAD.
New wearable cardiac acoustic monitoring technology for evaluation of subclinical leaflet thrombosis after transcatheter aortic valve replacement.
Heart
December 2024
Interventional Center of Valvular Heart Disease, Beijing Anzhen Hospital Affiliated to Capital Medical University, Beijing, China
Background: Subclinical leaflet thrombosis (SLT) is a common complication after transcatheter aortic valve replacement (TAVR). Multidimensional CT (MDCT) is the main imaging mortality for the diagnosis of SLT but it enhances the risk of contrast-induced nephropathy. Our study aimed to use an innovative wearable acoustic cardiography (ACG) device to diagnose SLT as an alternative option.
View Article and Find Full Text PDFComparing FFR-Guided Complete Revascularization and Conservative Management for Non-Culprit Lesions in STEMI Patients With Multivessel Disease: A Systematic Review and Meta-Analysis.
Catheter Cardiovasc Interv
December 2024
Department of Interventional Cardiology, Lancashire Cardiac Centre, Blackpool, UK.
Background: In patients with ST-segment elevation myocardial infarction (STEMI) and multivessel coronary artery disease, the optimal management strategy for non-culprit lesions is a subject of ongoing debate. There has been an increasing use of physiology-guidance to assess the extent of occlusion in non-culprit lesions, and hence the need for stenting. Fractional flow reserve (FFR) is commonly used as a technique.
View Article and Find Full Text PDFOptical coherence tomography-guided versus angiography-guided percutaneous coronary intervention for patients with complex lesions (OCCUPI): an investigator-initiated, multicentre, randomised, open-label, superiority trial in South Korea.
Lancet
September 2024
Division of Cardiology, Severance Cardiovascular Hospital, Yonsei University College of Medicine, Seoul, South Korea. Electronic address:
Article Synopsis
- The OCCUPI trial aimed to determine if optical coherence tomography (OCT) guidance during percutaneous coronary intervention (PCI) provides better clinical outcomes compared to traditional angiography guidance for complex heart lesions over a year.
- Conducted across 20 hospitals in South Korea, the trial included 1,604 patients aged 19-85 and utilized randomization to assign participants to either OCT or angiography guidance during their PCI procedure.
- The main outcome measured was the rate of major adverse cardiac events, but the effectiveness of OCT guidance in reducing these events compared to angiography guidance remains uncertain, as the study was designed to assess potential clinical benefits.
Systematic review and meta-analysis comparing complete versus incomplete or culprit-only revascularization by percutaneous coronary intervention in elderly patients with acute coronary syndrome.
Curr Probl Cardiol
December 2024
Department of Internal Medicine, Cleveland Clinic Foundation, Cleveland, OH, USA. Electronic address:
Article Synopsis
- * A meta-analysis involving 14 studies and over 62,000 patients found that CR significantly reduces all-cause mortality, cardiovascular-related mortality, and risk of myocardial infarction in elderly patients undergoing percutaneous coronary intervention (PCI).
- * Despite the benefits of CR, there were no significant differences in risks for stroke, major bleeding, stent thrombosis, or kidney injury, suggesting CR is a safe option for this population.
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