False-Positive PET/CT After Cyanoacrylate Sealing of a Pancreaticojejunostomy.

J Gastrointest Surg

Department of Surgery, St. Josef Hospital, Ruhr University of Bochum, Gudrunstr. 56, 44791, Bochum, Germany,

Published: May 2015

AI Article Synopsis

  • - In 2013, a 68-year-old man underwent surgery for pancreatic cancer and had a critical joint (pancreaticojejunostomy) sealed with a medical adhesive (Dermabond) to avoid complications.
  • - Eighteen months later, imaging tests suggested cancer recurrence at the surgical site, leading to another surgery where the sealed joint was removed.
  • - Histopathology revealed no cancer but significant inflammation due to Dermabond, indicating that the substance caused misleading imaging results and should not be used in cancer surgeries.

Article Abstract

In 2013, a 68-year-old male had a pancreaticoduodenectomy for pancreatic cancer. The pancreaticojejunostomy was sealed with cyanoacrylate (Dermabond) to prevent postoperative pancreatic fistula. Local recurrence of malignancy at the anastomosis was suspected 18 months later in PET/CT. Surgical revision was performed and anastomosis resected. However, histology showed no tumor recurrence, but strong inflammation and foreign-body reaction towards Dermabond. The sealant caused false-positive PET/CT findings, so its use in oncologic surgery should be abandoned.

Download full-text PDF

Source
http://dx.doi.org/10.1007/s11605-015-2780-9DOI Listing

Publication Analysis

Top Keywords

false-positive pet/ct
8
pet/ct cyanoacrylate
4
cyanoacrylate sealing
4
sealing pancreaticojejunostomy
4
pancreaticojejunostomy 2013
4
2013 68-year-old
4
68-year-old male
4
male pancreaticoduodenectomy
4
pancreaticoduodenectomy pancreatic
4
pancreatic cancer
4

Similar Publications

Radical prostatectomy without prostate biopsy based on a noninvasive diagnostic strategy: a prospective single-center study.

Prostate Cancer Prostatic Dis

December 2024

Department of Urology, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.

Background: Prostate biopsy is the most common approach for diagnosing prostate cancer (PCa); however, it has inherent limitations, such as the invasive procedure, postoperative complications, and false negative results. We aimed to provide a noninvasive diagnostic strategy for patients with highly suspected PCa and to evaluate the feasibility of performing biopsy-spared radical prostatectomy.

Methods: This prospective study included a total of 57 patients between November 10, 2022, and December 1, 2023.

View Article and Find Full Text PDF

A 62-year-old man, previously treated for oral cavity carcinoma, presented with new-onset cognitive-motor symptoms. Brain MRI revealed a periventricular, avidly enhancing lesion in the right anterior basal ganglia and hypothalamus suspicious for a brain tumor, particularly CNS lymphoma. 18F-FDG brain PET/CT showed corresponding uptake suggestive of primary brain tumor, lymphoma, or metastasis.

View Article and Find Full Text PDF

Lung cancer is the leading cause of cancer-related deaths globally. Despite recent improvements in incidence and mortality rates, the prognosis of lung cancer remains dire.F-FDG PET/CT plays a vital role in diagnosing, staging, and monitoring the therapeutic efficacy of lung cancer.

View Article and Find Full Text PDF

Longitudinal Evaluation of FDG Uptake in a Synovial Herniation Pit in 8 Years: Implications for Potential False-Positive PET Findings.

Clin Nucl Med

December 2024

From the Division of Nuclear Medicine and Molecular Imaging, Department of Radiology and Imaging Sciences, Emory University School of Medicine, Atlanta, GA.

Synovial herniation pit, also known as Pitt's pit, is a benign osseous lesion incidentally seen on imaging studies. Most of them will not show FDG uptake, but some herniation pits could show intense FDG uptake on PET/CT scans mimicking osseous metastasis. Here we report a case of synovial herniation pit in a patient with T-cell lymphoma through 8-year trajectory of FDG PET/CT scans, revealing its changing FDG uptake in relation to chemotherapy and final outcome.

View Article and Find Full Text PDF

To compare the diagnostic value of [F]AlF-LNC1007, [F]FDG, and [F]AlF-NOTA-FAPI-04 PET/CT in breast cancer. 33 patients with highly suspected or already diagnosed but untreated breast cancer were enrolled in the study and underwent [F]AlF-LNC1007 (30 patients), [F]FDG (22 patients), and [F]AlF-NOTA-FAPI-04 (8 patients) PET/CT. Quantitative measurements included the SUV and tumor-to-background ratio (TBR) for all lesions and background tissues.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!

A PHP Error was encountered

Severity: Notice

Message: fwrite(): Write of 34 bytes failed with errno=28 No space left on device

Filename: drivers/Session_files_driver.php

Line Number: 272

Backtrace:

A PHP Error was encountered

Severity: Warning

Message: session_write_close(): Failed to write session data using user defined save handler. (session.save_path: /var/lib/php/sessions)

Filename: Unknown

Line Number: 0

Backtrace: