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[Long-term control of stage IV breast and gastric cancer with combination therapy of S-1 and paclitaxel]. | LitMetric

AI Article Synopsis

  • - A 50-year-old woman was diagnosed with Stage IV breast cancer and gastric cancer, and began treatment with local radiation and tamoxifen after finding multiple bone metastases.
  • - Due to worsening symptoms like pain, nausea, and fatigue, she switched to S-1/paclitaxel therapy, which is a combination of two chemotherapy drugs.
  • - This new treatment resulted in reduced tumor size and significantly improved her quality of life (QOL) for 28 months without major side effects.

Article Abstract

We here describe a case of Stage IV breast and gastric cancer in which S-1/paclitaxel therapy was effective in maintaining the patient's QOL. A 50-year-old woman visited our hospital with complaints of her right breast tumor and right brachialgia. She was diagnosed with breast cancer with multiple bone metastases including cervical vertebrae. Accordingly, local radiation therapy and tamoxifen(TAM)administration was started immediately. Gastrointestinal endoscopy revealed gastric cancer, but laparotomy disclosed the gastric cancer was unresectable. At that time, the complaints of pain, nausea, and fatigue had increased and S-1/paclitaxel therapy was started immediately. The treatment reduced the size of the lesions in the breast and stomach and improved the QOL without serious adverse events. We have been maintaining partial response(PR)in this patient for 28 months.

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Publication Analysis

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