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Congenital tuberculosis: presentation of a rare case. | LitMetric

AI Article Synopsis

  • * Diagnosis is challenging due to vague symptoms, and the case study presents a 48-day-old infant showing severe respiratory distress and other signs of illness after ineffective antibiotic treatment.
  • * After confirming tuberculosis through testing, treatment began, but unfortunately, the infant died shortly after due to the severe nature of the disease.

Article Abstract

Congenital tuberculosis is a rare disease with a high mortality rate. Congenital tuberculosis is considered the result of mother-to-child transmission from the placenta to the fetus, through the ingestion of the amniotic fluid, or via transplacental transmission through the umbilical vein. Given the non-specific clinical signs of tuberculosis, it is usually difficult to diagnose it. The case of a 48-day-old male infant hospitalized due to weight loss, fever, cough, hemoptysis, and respiratory distress for the past 20 days, is presented. In this period, he had received broad spectrum antibiotics but with no improvement. A chest x-ray showed the presence of consolidation and a cavitary lesion in the upper and middle left lung fields. Mycobacterium tuberculosis was detected by polymerase chain reaction in a bronchoalveolar lavage specimen. Congenital tuberculosis was diagnosed based on this finding; hence, a tuberculostatic regimen was started accordingly. The patient died 13 days after treatment initiation. Congenital tuberculosis should be considered in infants with weight loss, fever, cough, hemoptysis and respiratory distress.

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Source
http://dx.doi.org/10.5546/aap.2015.eng.e101DOI Listing

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