Introduction: Pituitary metastases are rare and difficult to diagnose. Their optimal approach and management remains to be defined.
Case Report: We report the case of a 56-year-old patient suffering from squamous cell lung carcinoma who developed pituitary metastasis with secondary hypopituitarism, the symptoms of which were initially attributed to depression.
Conclusion: Pituitary metastases can be difficult to diagnose, which may lead to delays in care, which can be fatal.
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http://dx.doi.org/10.1016/j.rmr.2014.11.071 | DOI Listing |
J Cancer Res Clin Oncol
December 2024
Department of Neurosurgery, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
Purpose: Analysis of autofluorescence holds promise for brain tumor delineation and diagnosis. Therefore, we investigated the potential of a commercial confocal laser scanning endomicroscopy (CLE) system for clinical imaging of brain tumors.
Methods: A clinical CLE system with fiber probe and 488 nm laser excitation was used to acquire images of tissue autofluorescence.
Front Horm Res
November 2024
School of Medicine, University of Bologna, Bologna, Italy.
Acta Neuropathol
November 2024
Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden.
Endocr Pathol
December 2024
Department of Pathology, University of California San Francisco (UCSF), 505 Parnassus Avenue, Room M-559, San Francisco, CA, 94143, USA.
High-grade or grade 3 epithelial neuroendocrine neoplasms (G3 NEN) are now divided into grade 3 well-differentiated neuroendocrine tumor (G3 NET) and neuroendocrine carcinoma (NEC), both defined by Ki-67 > 20% and/or > 20 mitoses per 2 mm. NET and NEC are thought to be distinct tumors with different genetic profiles: NEC classically harbors co-alteration of TP53 and RB1, whereas NET genetics are site-dependent with frequent alterations in MEN1, ATRX, DAXX, and TSC1/2 in pancreatic NETs. Progression from NET to NEC is considered rare and is not well described.
View Article and Find Full Text PDFGland Surg
October 2024
Laboratory of Cellular and Molecular Biology, School of Basic Medicine, Central South University, Changsha, China.
Background: Breast cancer is one of the most common malignant tumors, occurring in the mammary glands, which often metastasizes to bones, lungs, and liver. However, pituitary metastasis (PM) originating from breast cancer is a rare phenomenon that can easily be mistaken for benign pituitary macroadenoma.
Case Description: This report details two cases of middle-aged and elderly Chinese women who presented with serious neurological symptoms, each with a history of breast malignancy.
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