Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4530052 | PMC |
| http://dx.doi.org/10.1016/j.jaci.2014.12.1941 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Tumor microenvironment-based signatures distinguish intratumoral heterogeneity, prognosis, and immunogenomic features of clear cell renal cell carcinoma.
J Natl Cancer Cent
September 2023
Department of Urology, Fudan University Shanghai Cancer Center; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China.
Background: The tumor microenvironment (TME) performs a crucial function in the tumorigenesis and response to immunotherapies of clear cell renal cell carcinoma (ccRCC). However, a lack of recognized pre-clinical TME-based risk models poses a great challenge to investigating the risk factors correlated with prognosis and treatment responses for patients with ccRCC.
Methods: Stromal and immune contexture were assessed to calculate the TMErisk score of a large sample of patients with ccRCC from public and real-world cohorts using machine-learning algorithms.
Identification of hub genes associated with somatic cell score in dairy cow.
Trop Anim Health Prod
October 2023
Department of Animal Science, Faculty of Agricultural Science, Payame Noor University, Tehran, 19395-4697, Iran.
Context: Somatic cell count (SCC) is used as an indicator of udder health. The log transformation of SCC is called somatic cell score (SCS).
Aim: Several QTL and genes have been identified that are associated with SCS.
A novel signature based on pyroptosis-related genes for predicting prognosis and treatment response in prostate cancer patients.
Front Genet
October 2022
Department of Urology, Lanzhou University Second Hospital, Lanzhou, China.
Pyroptosis is a form of programmed cell death accompanied by specific inflammatory and immune responses, and it is closely related to the occurrence and progression of various cancers. However, the roles of pyroptosis-related genes (PRGs) in the prognosis, treatment response, and tumor microenvironment (TME) of prostate cancer (PCa) remain to be investigated. The mRNA expression data and clinical information of PCa patients were obtained from the Cancer Genome Atlas database (TCGA) and the cBioPortal for Cancer Genomics website, and the 52 PRGs were obtained from the published papers.
View Article and Find Full Text PDFIdentification of SNPs Associated with Somatic Cell Score in Candidate Genes in Italian Holstein Friesian Bulls.
Animals (Basel)
February 2021
Department of Veterinary Science, University of Turin, 10095 Grugliasco (Turin), Italy.
Mastitis is an infectious disease affecting the mammary gland, leading to inflammatory reactions and to heavy economic losses due to milk production decrease. One possible way to tackle the antimicrobial resistance issue stemming from antimicrobial therapy is to select animals with a genetic resistance to this disease. Therefore, aim of this study was to analyze the genetic variability of the SNPs found in candidate genes related to mastitis resistance in Holstein Friesian bulls.
View Article and Find Full Text PDFSomatic mutations and T-cell clonality in patients with immunodeficiency.
Haematologica
December 2020
Hematology Research Unit Helsinki, University of Helsinki, HUS, Helsinki, Finland.
Common variable immunodeficiency and other late-onset immunodeficiencies often co-manifest with autoimmunity and lymphoproliferation. The pathogenesis of most cases is elusive, as only a minor subset harbors known monogenic germline causes. The involvement of both B and T cells is however implicated.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!