In this issue of Blood, Appelmann et al provide evidence for prolonged survival and prevention of resistance in a mouse model of Philadelphia chromosome–positive (Ph+) acute lymphoblastic leukemia (ALL) by combined targeting of the BCR-ABL kinase and Janus kinase 2 (JAK2) with dasatinib and ruxolitinib, respectively.

Download full-text PDF

Source
http://dx.doi.org/10.1182/blood-2014-12-617548DOI Listing

Publication Analysis

Top Keywords

targeting bcr-abl
8
bcr-abl jak2
4
jak2 ph+
4
ph+ issue
4
issue blood
4
blood appelmann
4
appelmann provide
4
provide evidence
4
evidence prolonged
4
prolonged survival
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!