Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1038/ncb3123 | DOI Listing |
Publication Analysis
Top Keywords
trio-rac1-pak1 signalling
4
signalling axis
4
axis drives
4
drives invadopodia
4
invadopodia disassembly
4
trio-rac1-pak1
1
axis
1
drives
1
invadopodia
1
disassembly
1
Similar Publications
A Trio-Rac1-Pak1 signalling axis drives invadopodia disassembly.
Nat Cell Biol
June 2014
Department of Anatomy and Structural Biology, Gruss-Lipper Biophotonics Center, Albert Einstein College of Medicine of Yeshiva University, Bronx, New York 10461, USA.
Rho family GTPases control cell migration and participate in the regulation of cancer metastasis. Invadopodia, associated with invasive tumour cells, are crucial for cellular invasion and metastasis. To study Rac1 GTPase in invadopodia dynamics, we developed a genetically encoded, single-chain Rac1 fluorescence resonance energy (FRET) transfer biosensor.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!