Chronic myeloid leukemia diagnosed in a patient with uncontrolled proliferative diabetic retinopathy.

Purpose: To report a case of uncontrolled proliferative diabetic retinopathy as an initial manifestation of chronic myeloid leukemia.

Methods: Case report.

Patients: A 55-year-old man with moderate nonproliferative diabetic retinopathy who rapidly developed proliferative retinopathy and bilateral neovascular glaucoma despite good glycemic control.

Conclusion: Other pathologies should be excluded in diabetic patients with a rapid and severe progression in their retinopathy despite adequate metabolic control. These patients should be treated promptly and aggressively until systemic disease is stable.