Background: Short-term exposure to air pollution has adverse effects among patients with asthma, but whether long-term exposure to air pollution is a cause of adult-onset asthma is unclear.
Objective: We aimed to investigate the association between air pollution and adult onset asthma.
Methods: Asthma incidence was prospectively assessed in six European cohorts. Exposures studied were annual average concentrations at home addresses for nitrogen oxides assessed for 23,704 participants (including 1,257 incident cases) and particulate matter (PM) assessed for 17,909 participants through ESCAPE land-use regression models and traffic exposure indicators. Meta-analyses of cohort-specific logistic regression on asthma incidence were performed. Models were adjusted for age, sex, overweight, education, and smoking and included city/area within each cohort as a random effect.
Results: In this longitudinal analysis, asthma incidence was positively, but not significantly, associated with all exposure metrics, except for PMcoarse. Positive associations of borderline significance were observed for nitrogen dioxide [adjusted odds ratio (OR) = 1.10; 95% CI: 0.99, 1.21 per 10 μg/m3; p = 0.10] and nitrogen oxides (adjusted OR = 1.04; 95% CI: 0.99, 1.08 per 20 μg/m3; p = 0.08). Nonsignificant positive associations were estimated for PM10 (adjusted OR = 1.04; 95% CI: 0.88, 1.23 per 10 μg/m3), PM2.5 (adjusted OR = 1.04; 95% CI: 0.88, 1.23 per 5 μg/m3), PM2.5absorbance (adjusted OR = 1.06; 95% CI: 0.95, 1.19 per 10-5/m), traffic load (adjusted OR = 1.10; 95% CI: 0.93, 1.30 per 4 million vehicles × meters/day on major roads in a 100-m buffer), and traffic intensity (adjusted OR = 1.10; 95% CI: 0.93, 1.30 per 5,000 vehicles/day on the nearest road). A nonsignificant negative association was estimated for PMcoarse (adjusted OR = 0.98; 95% CI: 0.87, 1.14 per 5 μg/m3).
Conclusions: Results suggest a deleterious effect of ambient air pollution on asthma incidence in adults. Further research with improved personal-level exposure assessment (vs. residential exposure assessment only) and phenotypic characterization is needed.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4455584 | PMC |
| http://dx.doi.org/10.1289/ehp.1408206 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Role of stomatal and leaf anatomical features in defining plant performance under elevated carbon dioxide and ozone, in the changing climate scenario.
Environ Sci Pollut Res Int
January 2025
Laboratory of Ecotoxicology, Department of Botany, Institute of Science, Banaras Hindu University, Varanasi, 221005, India.
This research investigates the interactive effects of elevated ozone (eO) and carbon dioxide (eCO) on stomatal morphology and leaf anatomical characteristics in two wheat cultivars with varying O sensitivities. Elevated O increased stomatal density and conductance, causing oxidative stress and cellular damage, particularly in the O-sensitive cultivar PBW-550 (PW), compared to HUW-55 (HW). Conversely, eCO reduced stomatal density and pore size, mitigating O-induced damage by limiting O influx.
View Article and Find Full Text PDFRecent developments on aerial lab-on-a-drone platforms for remote environmental monitoring: A review.
Anal Chim Acta
February 2025
Instituto de Química, Universidade Federal de Goiás, 74690-900, Goiânia, GO, Brazil; Instituto Nacional de Ciência e Tecnologia de Bioanalítica, Campinas, 13084-971, SP, Brazil. Electronic address:
Background: Distinct classes of environmental contaminants - such as microplastics, volatile organic compounds, inorganic gases, hormones, pesticides/herbicides, and heavy metals - have been continuously released into the environment from different sources. Anthropogenic activities with unprecedented consequences have impacted soil, surface waters, and the atmosphere. In this scenario, developing sensing materials and analytical platforms for monitoring water and air quality is essential to supporting worldwide environmental control agencies.
View Article and Find Full Text PDFThe capacity of human interventions to regulate PM concentration has substantially improved in China.
Environ Int
January 2025
State Key Laboratory of Environmental Criteria and Risk Assessment, Chinese Research Academy of Environmental Sciences, Beijing 100012, China.
The rapid urbanization in China has brought about serious air pollution problems, which are likely to persist for a considerable period as the urbanization process continues. In urban areas, the spatial distribution of air pollutants represented by PM has been proved mainly affected by emission, urban landscape pattern (short as ULP), as well as meteorological conditions. However, the contributions of these factors can seriously vary with different periods of urban development.
View Article and Find Full Text PDFSources of PM exposure and health benefits of clean air actions in Shanghai.
Environ Int
January 2025
Jiangsu Key Laboratory of Atmospheric Environment Monitoring and Pollution Control, Collaborative Innovation Center of Atmospheric Environment and Equipment Technology, Joint International Research Laboratory of Climate and Environment Change, School of Environmental Science and Engineering, Nanjing University of Information Science and Technology, Nanjing 210044, China.
Estimating PM exposure and its health impacts in cities involves large uncertainty due to the limitations of model resolutions. Consequently, attributing the sources of PM-related health impacts at the city level remains challenging. We characterize the health impacts associated with chronic PM exposure and anthropogenic emissions in Shanghai using a chemical transport model (GEOS-Chem) and its adjoint.
View Article and Find Full Text PDFThe effect of short-term exposure to air pollution on the admission of ischemic stroke and its interaction with meteorological factors.
Public Health
January 2025
Department of Neurology, First Affiliated Hospital of Gannan Medical Univesity, Ganzhou, 341000, Jiangxi, China. Electronic address:
Objectives: The aim of this study was to investigate the associations, potential effects, and interactions between short-term exposure to air pollution and the risk of ischemic stroke (IS).
Study Design: An ecological study.
Methods: Daily data on IS incidents, air pollution, and meteorological conditions were collected from 2017 to 2021 in Gannan.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!