AI Article Synopsis
- Vaspin is an adipokine linked to vascular issues, and this study looked at its relationship with systemic sclerosis (SSc)
- 12% of participants showed high serum vaspin levels (over 10 ng/mL), possibly due to genetic factors
- SSc patients with digital ulcers had lower serum vaspin levels compared to those without ulcers, indicating vaspin might play a role in these ulcers
Article Abstract
Vaspin is an adipokine implicated in vascular inflammation and remodeling. We herein evaluated the clinical correlation of serum vaspin levels in systemic sclerosis (SSc). Consistent with previous reports, 12% of subjects exhibited serum vaspin levels over 10 ng/mL, likely due to genetic effects. Excluding these subjects, despite no difference between SSc and control subjects, serum vaspin levels were significantly decreased in SSc patients with digital ulcers compared with those without, suggesting the potential contribution of vaspin to digital ulcers of this disease.
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| http://dx.doi.org/10.1111/1346-8138.12810 | DOI Listing |
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Serum levels of visfatin and vaspin in healthy and complicated pregnancies and their association with anthropometric measures of their offspring.
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College of Medicine, University of Tikrit, Iraq.
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