Effects of permafrost microorganisms on skin wound reparation.

Bull Exp Biol Med

Tyumen' Research Center, Siberian Division of the Russian Academy of Sciences, Tyumen, Russia,

Published: February 2015

Local application of ointment with Bacillus spp. strain MG8 (15,000-20,000 living bacterial cells), isolated from permafrost specimens, on the skin wound of about 60 mm(2) stimulated the reparation processes in experimental mice. A possible mechanism stimulating the regeneration of the damaged tissues under the effect of MG8 could be modulation of the immune system reactivity with more rapid switchover to humoral immunity anti-inflammatory mechanisms aimed at de novo synthesis of protein.

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http://dx.doi.org/10.1007/s10517-015-2789-9DOI Listing

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