AI Article Synopsis
- Movement disorders, specifically hemichorea-hemiballism (HCHB), can occur as complications following a stroke.
- A patient case study revealed HCHB linked to an acute infarction in both the corona radiata and cortex, even though the basal ganglia appeared unaffected on MRI.
- The cause of the cortical HCHB may stem from reduced blood flow to the basal ganglia or disrupted connections between the cerebral cortex and basal ganglia.
Article Abstract
Movement disorders are a recognized complication of stroke. Here we present a case of hemichorea-hemiballism (HCHB) after stroke. Basal ganglia and thalamus are typically recognized as sites responsible for HCHB. The MRI scan showed acute infarction which was unexpectedly present in both sides of corona radiate and cortex, but not in basal ganglia. This cortical HCHB could have evolved due to hypoperfusion of basal ganglia undetectable at the MRI scan or due to interruption of excitatory connections from the cerebral cortex to basal ganglia.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1007/s12013-015-0608-6 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Teaching Video NeuroImage: Methamphetamine-Induced Basal Ganglia Toxicity Presenting as Parkinsonism.
Neurology
February 2025
Department of Neurology, Montefiore Medical Center, Bronx, NY.
Consciousness trajectories and functional independence after acute brain injury in children with prolonged disorder of consciousness.
Dev Med Child Neurol
January 2025
Department of Rehabilitation, Children's Hospital of Chongqing Medical University, Chongqing, China.
Aim: To explore the trajectories of consciousness recovery and prognosis-associated predictors in children with prolonged disorder of consciousness (pDoC).
Method: This single-centre, retrospective, observational cohort involved 134 (87 males, 47 females) children diagnosed with pDoC and hospitalized at the Department of Rehabilitation at the Children's Hospital of Chongqing Medical University in China. The median onset age was 30 (interquartile range [IQR] 18-54) months, with onset ages ranging from 3 to 164 months.
Astrocyte-derived exosomes regulate sperm miR-34c levels to mediate the transgenerational effects of paternal chronic social instability stress.
Epigenetics
December 2025
Department of Developmental, Molecular and Chemical Biology, Tufts University School of Medicine, Boston, MA, USA.
The effects of chronically stressing male mice can be transmitted across generations by stress-specific changes in their sperm miRNA content, which induce stress-specific phenotypes in their offspring. However, how each stress paradigm alters the levels of distinct sets of sperm miRNAs is not known. We showed previously that exposure of male mice to chronic social instability (CSI) stress results in elevated anxiety and reduced sociability specifically in their female offspring across multiple generations because it reduces miR-34c levels in sperm of stressed males and their unstressed male offspring.
View Article and Find Full Text PDFUnlabelled: Motivated behaviors are regulated by distributed forebrain networks. Traditional approaches have often focused on individual brain regions and connections that do not capture the topographic organization of forebrain connectivity. We performed co-injections of anterograde and retrograde tract tracers in rats to provide novel high-spatial resolution evidence of topographic connections that elaborate a previously identified closed-loop forebrain circuit implicated in affective and motivational processes.
View Article and Find Full Text PDFBackground: Writer's cramp (WC) dystonia is an involuntary movement disorder with distributed abnormalities in the brain's motor network. Prior studies established the potential for repetitive transcranial magnetic stimulation (rTMS) to either premotor cortex (PMC) or primary somatosensory cortex (PSC) to modify symptoms. However, clinical effects have been modest with limited understanding of the neural mechanisms hindering therapeutic advancement of this promising approach.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!